Allomatrine

Modify Date: 2025-08-23 16:08:01

Allomatrine structure	Common Name	Allomatrine
	CAS Number	641-39-4	Molecular Weight	347.364
	Density	1.4±0.1 g/cm3	Boiling Point	638.7±55.0 °C at 760 mmHg
	Molecular Formula	C₁₅H₂₄N₂O	Melting Point	106-107 â„ƒ
	MSDS	N/A	Flash Point	340.1±31.5 °C

Use of Allomatrine

Allomatrine ((+)-Allomatrine) is an alkaloid from the bark of Sophora japonica. Allomatrine has antinociceptive properties mediated mainly through the activation ofκ-opioid receptors[1][2].

Name	4-(2-Biphenylyl)-1-(hydroxymethyl)-10-oxa-4-azatricyclo[5.2.1.02,6]dec-8-ene-3,5-dione
Synonym	More Synonyms

Description	Allomatrine ((+)-Allomatrine) is an alkaloid from the bark of Sophora japonica. Allomatrine has antinociceptive properties mediated mainly through the activation ofκ-opioid receptors[1][2].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease
References	[1]. Long Pan, et al. Chemical Constituents of Alkaloids From the Bark of Sophora Japonica. Zhong Yao Cai. 2016 Sep;39(9):2027-9. [2]. Seiichi Kobashi , et al. Antinociceptive Effects of 1-acyl-4-dialkylaminopiperidine and 1-alkyl-4-dialkylaminopiperidine in Mice: Structure-Activity Relation Study of Matrine-Type Alkaloids. Biol Pharm Bull. 2002 Aug;25(8):1030-4.

Description

Allomatrine ((+)-Allomatrine) is an alkaloid from the bark of Sophora japonica. Allomatrine has antinociceptive properties mediated mainly through the activation ofκ-opioid receptors[1][2].

Related Catalog

Signaling Pathways >> Others >> Others

Research Areas >> Neurological Disease

References

[1]. Long Pan, et al. Chemical Constituents of Alkaloids From the Bark of Sophora Japonica. Zhong Yao Cai. 2016 Sep;39(9):2027-9.

[2]. Seiichi Kobashi , et al. Antinociceptive Effects of 1-acyl-4-dialkylaminopiperidine and 1-alkyl-4-dialkylaminopiperidine in Mice: Structure-Activity Relation Study of Matrine-Type Alkaloids. Biol Pharm Bull. 2002 Aug;25(8):1030-4.

Density	1.4±0.1 g/cm3
Boiling Point	638.7±55.0 °C at 760 mmHg
Melting Point	106-107 â„ƒ
Molecular Formula	C₁₅H₂₄N₂O
Molecular Weight	347.364
Flash Point	340.1±31.5 °C
Exact Mass	347.115753
PSA	66.84000
LogP	2.09
Vapour Pressure	0.0±2.0 mmHg at 25°C
Index of Refraction	1.666
Storage condition	2-8C