LSTc

Modify Date: 2024-01-10 07:33:49

LSTc Structure
LSTc structure
Common Name LSTc
CAS Number 64003-55-0 Molecular Weight 998.88400
Density N/A Boiling Point N/A
Molecular Formula C37H62N2O29 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of LSTc


LSTc (LS-tetrasaccharide c) is a human lactooligosaccharide presents on glycoproteins and glycolipids. LSTc is also a specific human JC polyomavirus (JCV) recognition motif. LSTc has good potential for the study of progressive multifocal leukoencephalopathy (PML)[1].

 Names

Name α-NEU5AC-[2
Synonym More Synonyms

 LSTc Biological Activity

Description LSTc (LS-tetrasaccharide c) is a human lactooligosaccharide presents on glycoproteins and glycolipids. LSTc is also a specific human JC polyomavirus (JCV) recognition motif. LSTc has good potential for the study of progressive multifocal leukoencephalopathy (PML)[1].
Related Catalog
In Vitro LSTc specifically engaged by JCV and inhibits JCV infection in SVG-A cells[1]. Cell Viability Assay[1] Cell Line: SVG-A cells Concentration: 5 mM (pretreat LSTc with JCV, then JCV-LST complexes are added to cells) Incubation Time: 1 h Result: Inhibited JCV infection.
References

[1]. Neu U, et al. Structure-function analysis of the human JC polyomavirus establishes the LSTc pentasaccharide as a functional receptor motif. Cell Host Microbe. 2010 Oct 21;8(4):309-19.  

 Chemical & Physical Properties

Molecular Formula C37H62N2O29
Molecular Weight 998.88400
Exact Mass 998.34400
PSA 502.25000

 Synonyms

N-ACETYLNEURAMIN-LACTO-N-NEO-TETRAOSE C SODIUM SALT
LS-Tetrasaccharide c sodium salt
LS-Tetrasaccharide c,Sodium Salt,Human Milk
4]-GLC SODIUM SALT
SIALYLLACTO-N-NEOTETRAOSE-C
N-acetylneuraminyl-lacto-N-neo-tetraose C sodium
LST C SODIUM SALT
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