Ocrelizumab

Modify Date: 2024-01-10 07:39:45

Ocrelizumab Structure
Ocrelizumab structure
Common Name Ocrelizumab
CAS Number 637334-45-3 Molecular Weight N/A
Density N/A Boiling Point N/A
Molecular Formula N/A Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Ocrelizumab


Ocrelizumab is an anti-CD20 antibody that depletes circulating immature and mature B cells but spares CD20-negative plasma cells. The effector mechanisms of Ocrelizumab are complement-dependent cytotoxicity and antibody-dependent cellular cytotoxicity. Ocrelizumab is the first monoclonal antibody for secondary primary progressive multiple sclerosis (PPMS)[1].

 Names

Name Ocrelizumab
Synonym More Synonyms

 Ocrelizumab Biological Activity

Description Ocrelizumab is an anti-CD20 antibody that depletes circulating immature and mature B cells but spares CD20-negative plasma cells. The effector mechanisms of Ocrelizumab are complement-dependent cytotoxicity and antibody-dependent cellular cytotoxicity. Ocrelizumab is the first monoclonal antibody for secondary primary progressive multiple sclerosis (PPMS)[1].
Related Catalog
References

[1]. Mulero P, et al. Ocrelizumab: a new milestone in multiple sclerosis therapy. Ther Adv Neurol Disord. 2018 May 10;11:1756286418773025.  

 Chemical & Physical Properties

No Any Chemical & Physical Properties

 Synonyms

Monoclonal antibody Pro70769
Pro-70769
Pro70769
Rhumab 2H7
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