637334-45-3
637334-45-3 structure
- Name: Ocrelizumab
- Chemical Name: Ocrelizumab
- CAS Number: 637334-45-3
- Molecular Formula:
- Molecular Weight:
- Catalog: Research Areas Inflammation/Immunology
- Create Date: 2018-12-18 20:17:15
- Modify Date: 2025-09-17 20:04:38
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Ocrelizumab is an anti-CD20 antibody that depletes circulating immature and mature B cells but spares CD20-negative plasma cells. The effector mechanisms of Ocrelizumab are complement-dependent cytotoxicity and antibody-dependent cellular cytotoxicity. Ocrelizumab is the first monoclonal antibody for secondary primary progressive multiple sclerosis (PPMS)[1].
| Name | Ocrelizumab |
|---|---|
| Synonyms |
Monoclonal antibody Pro70769
Pro-70769 Pro70769 Rhumab 2H7 |
| Description | Ocrelizumab is an anti-CD20 antibody that depletes circulating immature and mature B cells but spares CD20-negative plasma cells. The effector mechanisms of Ocrelizumab are complement-dependent cytotoxicity and antibody-dependent cellular cytotoxicity. Ocrelizumab is the first monoclonal antibody for secondary primary progressive multiple sclerosis (PPMS)[1]. |
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| No Any Chemical & Physical Properties |