Cicloprolol hydrochloride

Modify Date: 2024-01-03 18:07:30

Cicloprolol hydrochloride structure	Common Name	Cicloprolol hydrochloride
	CAS Number	63686-79-3	Molecular Weight	359.888
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₈H₃₀ClNO₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Cicloprolol hydrochloride

Cicloprolol is a partial β 1-adrenoceptor agonist .

Name	Cicloprolol hydrochloride
Synonym	More Synonyms

Description	Cicloprolol is a partial β 1-adrenoceptor agonist .
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Adrenergic Receptor Research Areas >> Cardiovascular Disease
Target	Adrenoceptor[1]
In Vitro	Cicloprolol is a partial β1-adrenoceptor agonist considered for the treatment of patients with coronary artery disease and impaired left ventricular function[1]. The new β-adrenoceptor partial agonist Cicloprolol acts as a β-agonist at normal levels and as a β-antagonist at high levels of adrenergic discharge. Treatment with Cicloprolol should protect the heart against excessive stimulation, while providing a baseline level of sympathetic drive. Cicloprolol has a weak β1-agonistic effect at normal levels of adrenergic discharge and acts as an antagonist at high levels of discharge[2].
References	[1]. Weber S, et al. Pharmacodynamic without pharmacokinetic interaction between cicloprolol, a partial beta 1-adrenoceptor agonist, and digoxin in healthy subjects. Br J Clin Pharmacol. 1990 Sep;30(3):411-6 [2]. Cocco G, et al. An evaluation of the safety of the beta-modulator cicloprolol in chronic heart failure. Clin Cardiol. 1992 Jan;15(1):38-42.

(±)-1-(p-(2-(Cyclopropylmethoxy)ethoxy)phenoxy)-3-(isopropylamino)-2-propanol Hydrochloride

1-{4-[2-(Cyclopropylmethoxy)ethoxy]phenoxy}-3-(isopropylamino)-2-propanol hydrochloride (1:1)

2-Propanol, 1-[4-[2-(cyclopropylmethoxy)ethoxy]phenoxy]-3-[(1-methylethyl)amino]-, hydrochloride (1:1)

(±)-1-(4-(2-(Cyclopropylmethoxy)ethoxy)phenoxy)-3-((1-methylethyl)amino)-2-propanol Hydrochloride

cicloprolol hydrochloride

sl-d 177

UNII:T355YD4791

T355YD4791

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