7,8,9,10-Tetrahydrobenzo[pqr]tetraphen-7-ol
![7,8,9,10-Tetrahydrobenzo[pqr]tetraphen-7-ol Structure](https://www.chemsrc.com/caspic/338/6272-55-5.png)
7,8,9,10-Tetrahydrobenzo[pqr]tetraphen-7-ol structure
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Common Name | 7,8,9,10-Tetrahydrobenzo[pqr]tetraphen-7-ol | ||
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| CAS Number | 6272-55-5 | Molecular Weight | 272.340 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 508.5±19.0 °C at 760 mmHg | |
| Molecular Formula | C20H16O | Melting Point | 142-144ºC(lit.) | |
| MSDS | Chinese USA | Flash Point | 189.2±13.7 °C | |
Use of 7,8,9,10-Tetrahydrobenzo[pqr]tetraphen-7-ol7,8,9,10-Tetrahydrobenzo[a]pyren-7-ol is a benzopyrene derivative that is activated by hepatic cytosol into electrophilic sulfuric acid esters[1], which are capable of forming covalent DNA adducts and inducing mutations[2]. |
| Name | 7,8,9,10-tetrahydrobenzo[a]pyren-7-ol |
|---|---|
| Synonym | More Synonyms |
| Description | 7,8,9,10-Tetrahydrobenzo[a]pyren-7-ol is a benzopyrene derivative that is activated by hepatic cytosol into electrophilic sulfuric acid esters[1], which are capable of forming covalent DNA adducts and inducing mutations[2]. |
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| Related Catalog | |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 508.5±19.0 °C at 760 mmHg |
| Melting Point | 142-144ºC(lit.) |
| Molecular Formula | C20H16O |
| Molecular Weight | 272.340 |
| Flash Point | 189.2±13.7 °C |
| Exact Mass | 272.120117 |
| PSA | 20.23000 |
| LogP | 5.01 |
| Vapour Pressure | 0.0±1.4 mmHg at 25°C |
| Index of Refraction | 1.836 |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATAMUTATION DATA
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| Hazard Codes | Xn |
|---|---|
| RIDADR | NONH for all modes of transport |
| RTECS | DJ8304000 |
| HS Code | 2906299090 |
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7,8,9,10-Tetrah... CAS#:6272-55-5 |
| Literature: Klassen; Daub; Vanderjagt Journal of Organic Chemistry, 1983 , vol. 48, # 23 p. 4361 - 4366 |
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7,8,9,10-Tetrah... CAS#:6272-55-5 |
| Literature: Journal of the American Chemical Society, , vol. 63, p. 1682,1684 |
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7,8,9,10-Tetrah... CAS#:6272-55-5 |
| Literature: Journal of Organic Chemistry, , vol. 48, # 23 p. 4361 - 4366 |
|
~%
7,8,9,10-Tetrah... CAS#:6272-55-5 |
| Literature: Journal of Organic Chemistry, , vol. 48, # 23 p. 4361 - 4366 |
|
~%
7,8,9,10-Tetrah... CAS#:6272-55-5 |
| Literature: Journal of Organic Chemistry, , vol. 48, # 23 p. 4361 - 4366 |
|
~%
7,8,9,10-Tetrah... CAS#:6272-55-5 |
| Literature: Journal of Organic Chemistry, , vol. 48, # 23 p. 4361 - 4366 |
|
~%
7,8,9,10-Tetrah... CAS#:6272-55-5 |
| Literature: Journal of Organic Chemistry, , vol. 48, # 23 p. 4361 - 4366 |
|
~%
7,8,9,10-Tetrah... CAS#:6272-55-5 |
| Literature: Journal of Organic Chemistry, , vol. 48, # 23 p. 4361 - 4366 |
|
~%
7,8,9,10-Tetrah... CAS#:6272-55-5 |
| Literature: Journal of Organic Chemistry, , vol. 48, # 23 p. 4361 - 4366 |
| Precursor 9 | |
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| DownStream 2 | |
CAS#:50-32-8![9,10-dihydrobenzo[a]pyrene structure](https://www.chemsrc.com/caspic/421/17573-15-8.png)
CAS#:17573-15-8| HS Code | 2906299090 |
|---|---|
| Summary | 2906299090 other aromatic alcohols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0% |
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Synthesis of (+/-)-trans-7,8-Dihydrodiol of 6-Fluoro-benzo[a]pyrene via Hydroxyl-Directed Regioselective Functionalization of Substituted Pyrene.
J. Org. Chem. 64(6) , 1902-1907, (1999) Synthesis of (+/-)-trans-7,8-dihydroxy-6-fluoro-7,8-dihydrobenzo[a]pyrene, the metabolite from 6-fluoro-benzo[a]pyrene, is described. Position 6 of 7,8,9,10-tetrahydrobenzo[a]pyren-7-ol (1) was functi... |
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Recent Progress in the Use of N-Halo Compounds in Organic Synthesis. Veisi H, et al.
Org. Prep. Proced. Int. 43(6) , 489-540, (2011)
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Sulfotransferase-mediated activation of 7,8,9,10-tetrahydro-7-ol, 7,8-dihydrodiol, and 7,8,9,10-tetraol derivatives of benzo[a]pyrene.
Chem. Res. Toxicol. 8(5) , 693-8, (1995) Some hydroxymethyl-substituted polycyclic aromatic hydrocarbons have been shown to be converted to electrophilic, mutagenic, or tumorigenic sulfuric acid ester metabolites by cytosolic sulfotransferas... |
| 7,8,9,10-Tetrahydrobenzo[pqr]tetraphen-7-ol |
| MFCD00192475 |
| Benzo[a]pyren-7-ol, 7,8,9,10-tetrahydro- |