URANYL ACETATE DIHYDRATE

CAS#6159-44-0; 541-09-3
(anhydrous)
Manufacturer
RTECSYR3675000
SPECTRUM CHEMICAL MFG. CORP.
TSCA 8(b) inventory: No
TSCA
products were found. It is
exempt from TSCA 8(b)
Inventory listing since it is a
hydrate. However the
anhydrous form (CAS no.
541-06-3) is listed on the
TSCA 8(b) Inventory.
Commercial Name(s)Not available.
CI#Not available.
Bis(aceto)dioxouranium dihydrate;
Synonym
IN CASE OF EMERGENCY
Bis(aceto-O)dioxouranium, dihydrate;
Uranium, bis(aceto-O)dioxo-, dihydrate;
Uranyl (2+) acetate, dihydrate;
Uranium oxyacetate, dihydrate;
Uranium acetate, dihydrate;
Diacetatodioxouranium, dihydrate
Chemical NameNot available.
Not available.CALL (310) 516-8000
Chemical Family
Chemical FormulaUO2(CH3COO)2.H2O
SPECTRUM CHEMICAL MFG. CORP.

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Section 2.Composition and Information on Ingredients
Exposure Limits
NameCAS #TWA (mg/m3) STEL (mg/m3) CEIL (mg/m3) % by Weight
1) Uranyl acetate dihydrate6159-44-00.2 0.6100
Uranyl acetate dihydrate:
Toxicological Data
ORAL (LD50):Acute: 204 mg/kg [Rat]. 242 mg/kg [Mouse].
on Ingredients
Uranyl acetate dihydrate

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Section 3. Hazards Identification
Potential Acute HealthHazardous in case of ingestion, of inhalation. Slightly hazardous in case of skin contact (irritant), of eye
Effectscontact (irritant). Severe over-exposure can result in death.
CARCINOGENIC EFFECTS: Classified A1 (Confirmed for human.) by ACGIH.
Potential Chronic Health
MUTAGENIC EFFECTS: Not available.
Effects
TERATOGENIC EFFECTS: Not available.
DEVELOPMENTAL TOXICITY: Not available.
The substance may be toxic to kidneys, lungs, the nervous system, liver.
Repeated or prolonged exposure to the substance can produce target organs damage. Repeated exposure
to a highly toxic material may produce general deterioration of health by an accumulation in one or many
human organs.

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Section 4. First Aid Measures
Eye ContactCheck for and remove any contact lenses. Flush with plenty of water for at least 15 minutes, occasionally
lifting the upper and lower eyelids. Cold water may be used. Get medical attention if irritation occurs. Seek
medical attention in case of eye contact with a radioactive material.
Skin ContactWash with soap and water. Cover the irritated skin with an emollient. Get medical attention if irritation
develops. Cold water may be used.
Serious Skin ContactNot available.
InhalationIf inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Get medical attention immediately.
Serious InhalationEvacuate the victim to a safe area as soon as possible. Loosen tight clothing such as a collar, tie, belt or
waistband. If breathing is difficult, administer oxygen. If the victim is not breathing, perform mouth-to-mouth
resuscitation. WARNING: It may be hazardous to the person providing aid to give mouth-to-mouth
resuscitation when the inhaled material is toxic, infectious or corrosive. If breathing is difficult, administer
oxygen. If the victim is not breathing, perform mouth-to-mouth resuscitation. Seek medical attention in case
of inhalation of a radioactive material.
IngestionIf swallowed, do not induce vomiting unless directed to do so by medical personnel. Never give anything by
mouth to an unconscious person. Loosen tight clothing such as a collar, tie, belt or waistband. Get medical
attention immediately.
Serious IngestionNot available.

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Section 5. Fire and Explosion Data
Flammability of the Product May be combustible at high temperature.
Auto-Ignition Temperature Not available.
Flash PointsNot available.
Not available.
Flammable Limits
These products are carbon oxides (CO, CO2).
Products of Combustion
Fire Hazards in Presence of Slightly flammable to flammable in presence of heat.
Various Substances
Explosion Hazards inRisks of explosion of the product in presence of mechanical impact: Not available.
Presence of VariousRisks of explosion of the product in presence of static discharge: Not available.
Substances
SMALL FIRE: Use DRY chemical powder.
Fire Fighting Media
LARGE FIRE: Use water spray, fog or foam. Do not use water jet.
and Instructions
Not available.
Special Remarks on
Fire Hazards
Special Remarks on Explosion Not available.
Hazards
Uranyl acetate dihydrate

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Section 6. Accidental Release Measures
Small SpillUse appropriate tools to put the spilled solid in a convenient waste disposal container.
Large SpillRadioactive material.
Stop leak if without risk. Do not attempt recovery actions unless for rescue purposes. Do not touch
damaged container or spilled material. Do not clean-up or dispose except under supervision of a specialist.
Avoid contact with a combustible material (wood, paper, oil, clothing...). Prevent entry into sewers,
basements or confined areas; dike if needed. Eliminate all ignition sources. Be careful that the product is
not present at a concentration level above TLV. Check TLV on the MSDS and with local authorities.

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Section 7. Handling and Storage
Keep away from heat. Keep away from sources of ignition. Ground all equipment containing material. Do
Precautions
not breathe dust. If ingested, seek medical advice immediately and show the container or the label. Avoid
contact with skin and eyes
Radioactive materials should be stored in a separate safety storage cabinet or room.
Storage

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Section 8. Exposure Controls/Personal Protection
Engineering ControlsUse process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels
below recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep
exposure to airborne contaminants below the exposure limit.
Personal ProtectionSafety glasses. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent.
Gloves. Suggested protective clothing might not be sufficient; consult a specialist BEFORE handling this
product.
Personal Protection in Case of Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self contained breathing apparatus should be
a Large Spillused to avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a
specialist BEFORE handling this product.
TWA: 0.05 (mg/m3) (as U) from OSHA (PEL) [United States] (Uranium soluble compounds)
Exposure Limits
TWA: 0.2 STEL: 0.6 (as U) (mg/m3) from ACGIH (TLV) [United States] (Uranium compounds, n.o.s)
TWA: 0.05 (mg/m3) (as U) from NIOSH [United States] (Uranium soluble compounds)
TWA: 0.2 STEL: 0.6 (as U) (mg/m3) [Canada]
Consult local authorities for acceptable exposure limits.

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Section 9. Physical and Chemical Properties
Physical state and appearance Solid. (Crystalline solid.)OdorAcetic acid. (Slight.)
Not available.
Taste
424.15 g/mole
Molecular Weight
ColorYellow.
pH (1% soln/water)Not available.
Boiling PointNot available.
Melting Point110°C (230°F)
Deomposition Temperature: 275 deg. C
Critical TemperatureNot available.
Specific Gravity2.893 (Water = 1)
Vapor PressureNot applicable.
Not available.
Vapor Density
VolatilityNot available.
Not available.
Odor Threshold
Water/Oil Dist. Coeff.Not available.
Ionicity (in Water)Not available.
Dispersion PropertiesSee solubility in water.
Uranyl acetate dihydrate
Partially soluble in cold water.
Solubility
Freely soluble in water acidulated with acetic acid.
Solubility in water: 7.694 g/100 ml @ 15 deg. C.
Decomposes in hot water.
Soluble in 10 parts of water, usually incompletely, due to the presence of the basic salt.
Very soluble in alcohol.

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Section 10. Stability and Reactivity Data
The product is stable.
Stability
Instability TemperatureNot available.
Conditions of InstabilityExcess heat, incompatible materials
Incompatibility with various Reactive with oxidizing agents.
substances
Non-corrosive in presence of glass.
Corrosivity
Special Remarks onNot available.
Reactivity
Special Remarks onNot available.
Corrosivity
PolymerizationNo.

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Section 11. Toxicological Information
Routes of EntryInhalation. Ingestion.
Toxicity to AnimalsAcute oral toxicity (LD50): 204 mg/kg [Rat].
Chronic Effects on Humans May cause damage to the following organs: kidneys, lungs, the nervous system, liver.
Other Toxic Effects onHazardous in case of ingestion, of inhalation.
HumansSlightly hazardous in case of skin contact (irritant).
Special Remarks onNot available.
Toxicity to Animals
Special Remarks onMay cause adverse reproductive effects and birth defects (teratogenic).
Chronic Effects on Humans May cause cancer
Special Remarks on otherRadioactive Material with low specific activity.
Toxic Effects on HumansAcute Potential Health Effects:
Skin: May cause skin irritation.
Eyes: May cause eye irritation.
Inhalation: May be harmful by inhalation. May cause respiratory tract (nose, throat, lungs) and mucous
membrane irritation. Symptoms may include coughing, wheezing and/or shortness of breath.
Ingestion: Harmful if swallowed. May affect behavior/central nervous system (tremor), blood (changes in
serum composition, anemia), metabolism (loss of appetite), urinary system (renal function tests depressed)
Chronic Potential Health Effects:
Ingestion: Danger of cumulative effects. May affect blood (changes in red blood cell count, changes in
blood serum composition, anemia), metabolism (weight loss), liver, brain.

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Section 12. Ecological Information
EcotoxicityNot available.
BOD5 and CODNot available.
Products of BiodegradationPossibly hazardous short term degradation products are not likely. However, long term degradation
products may arise.
The products of degradation are as toxic as the original product.
Toxicity of the Products
of Biodegradation
Uranyl acetate dihydrate
Not available.
Special Remarks on the
Products of Biodegradation

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Section 13. Disposal Considerations
Waste DisposalWaste must be disposed of in accordance with federal, state and local environmental
control regulations.

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Section 14. Transport Information
DOT ClassificationCLASS 7: Radioactive material.
UNNA: 2910: Radioactive material, excepted package-limited quantity of material (Uranyl Acetate dihydrate)
Identification
PG: Not available.
Not available.
Special Provisions for
Transport
DOT (Pictograms)

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Section 15. Other Regulatory Information and Pictograms
Federal and StateCalifornia prop. 65: This product contains the following ingredients for which the State of California has
found to cause cancer, birth defects or other reproductive harm, which would require a warning under the
Regulations
statute: Uranyl acetate dihydrate
California prop. 65: This product contains the following ingredients for which the State of California has
found to cause cancer which would require a warning under the statute: Uranyl acetate dihydrate
New York release reporting list: Uranyl acetate
Pennsylvania RTK: Uranyl acetate
Minnesota: Uranyl acetate dihydrate (Listed as Uranium soluble compounds)
Massachusetts RTK: Uranyl acetate
New Jersey: Uranyl acetate
New Jersey spill list: Uranyl acetate
Louisiana spill reporting: Uranyl acetate
California Director's List of Hazardous Substances: Uranyl acetate dihydrate (Listed as Uranium
compounds, n.o.s)
TSCA 8(b) inventory: No products were found.
CERCLA: Hazardous substances.: Uranyl acetate: 100 lbs. (45.36 kg)
CaliforniaCalifornia prop. 65: This product contains the following ingredients for which the State of California has
Proposition 65found to cause cancer which would require a warning under the statute: Uranyl acetate dihydrate
Warnings
California prop. 65: This product contains the following ingredients for which the State of California has
found to cause birth defects which would require a warning under the statute: No products were found.
Other RegulationsOSHA: Hazardous by definition of Hazard Communication Standard (29 CFR 1910.1200).
EINECS: This product is not on the European Inventory of Existing Commercial Chemical Substances.
Canada: Not listed on Canadian Domestic Substance List (DSL) or Canadian Non- Domestic Substance
List (NDSL).
China: Listed on National Inventory.
Japan: Not listed on National Inventory (ENCS).
Korea: Not listed on National Inventory (KECI).
Philippines: Not listed on National Inventory (PICCS).
Australia: Listed on AICS.
Other ClassificationsWHMIS (Canada) Not controlled under WHMIS (Canada).
DSCL (EEC)R26/28- Very toxic by inhalation andS20/21- When using do not eat, drink or
if swallowed.smoke.
R33- Danger of cumulative effects.S45- In case of accident or if you feel unwell,
R51/53- Toxic to aquatic organisms,seek medical advice immediately (show the
may cause long-term adverse effectslabel where possible).
in the aquatic environment.S61- Avoid release to the environment.
Refer to special instructions/Safety data
sheets.
Uranyl acetate dihydrate
Health Hazard
HMIS (U.S.A.)2 National Fire Protection
1 Flammability
1 Association (U.S.A.)
Fire Hazard
2 0 Reactivity
Health
Reactivity
0
Specific hazard
Personal Protection
x
WHMIS (Canada)
(Pictograms)
DSCL (Europe)
(Pictograms)
TDG (Canada)
(Pictograms)
ADR (Europe)
(Pictograms)
Protective Equipment
Gloves.
Lab coat.
Dust respirator. Be sure to use an
approved/certified respirator or
equivalent. Wear appropriate respirator
when ventilation is inadequate.
Uranyl acetate dihydrate
CALL (310) 516-8000
Notice to Reader
All chemicals may pose unknown hazards and should be used with caution. This Material Safety Data Sheet (MSDS) applies only to the material as packaged. If this product is
combined with other materials, deteriorates, or becomes contaminated, it may pose hazards not mentioned in this MSDS. It shall be the user's responsibility to develop proper
methods of handling and personal protection based on the actual conditions of use. While this MSDS is based on technical data judged to be reliable, Spectrum Quality Products,

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SECTION 16 - ADDITIONAL INFORMATION
N/A

MOLECULAR FORMULA :

C4-H6-O6-U.2H2-O

MOLECULAR WEIGHT :

424.14

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

204 mg/kg

TOXIC EFFECTS :

Behavioral - tremor Skin and Appendages - hair Nutritional and Gross Metabolic - body temperature decrease

REFERENCE :

BECTA6 Bulletin of Environmental Contamination and Toxicology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1966- Volume(issue)/page/year: 39,168,1987

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Subcutaneous

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

8300 ug/kg

TOXIC EFFECTS :

Behavioral - tremor Skin and Appendages - hair Nutritional and Gross Metabolic - body temperature decrease

REFERENCE :

BECTA6 Bulletin of Environmental Contamination and Toxicology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1966- Volume(issue)/page/year: 39,168,1987

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

242 mg/kg

TOXIC EFFECTS :

Behavioral - tremor Skin and Appendages - hair Nutritional and Gross Metabolic - body temperature decrease

REFERENCE :

BECTA6 Bulletin of Environmental Contamination and Toxicology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1966- Volume(issue)/page/year: 39,168,1987

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Subcutaneous

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

20400 ug/kg

TOXIC EFFECTS :

Behavioral - tremor Skin and Appendages - hair Nutritional and Gross Metabolic - body temperature decrease

REFERENCE :

BECTA6 Bulletin of Environmental Contamination and Toxicology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1966- Volume(issue)/page/year: 39,168,1987

TYPE OF TEST :

LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :

Intravenous

SPECIES OBSERVED :

Rodent - guinea pig

DOSE/DURATION :

5350 ug/kg

TOXIC EFFECTS :

Kidney, Ureter, Bladder - changes in both tubules and glomeruli

REFERENCE :

TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 7,32,1965 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

448 mg/kg/4W-C

TOXIC EFFECTS :

Blood - changes in erythrocyte (RBC) count Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - transaminases Biochemical - Metabolism (Intermediary) - Plasma proteins not involving coagulation

REFERENCE :

BECTA6 Bulletin of Environmental Contamination and Toxicology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1966- Volume(issue)/page/year: 42,935,1989 ** REPRODUCTIVE DATA **

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

DOSE :

50 mg/kg

SEX/DURATION :

female 6-15 day(s) after conception

TOXIC EFFECTS :

Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Specific Developmental Abnormalities - musculoskeletal system

REFERENCE :

TXCYAC Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85, Limerick, Ireland) V.1- 1973- Volume(issue)/page/year: 55,143,1989

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

DOSE :

100 mg/kg

SEX/DURATION :

female 6-15 day(s) after conception

TOXIC EFFECTS :

Reproductive - Specific Developmental Abnormalities - craniofacial (including nose and tongue)

REFERENCE :

TXCYAC Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85, Limerick, Ireland) V.1- 1973- Volume(issue)/page/year: 55,143,1989

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

DOSE :

2 gm/kg

SEX/DURATION :

male 60 day(s) pre-mating female 2 week(s) pre-mating female 1-13 day(s) after conception

TOXIC EFFECTS :

Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Effects on Embryo or Fetus - fetal death

REFERENCE :

EESADV Ecotoxicology and Environmental Safety. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1977- Volume(issue)/page/year: 17,291,1989

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

DOSE :

990 mg/kg

SEX/DURATION :

male 60 day(s) pre-mating female 14 day(s) pre-mating - 4 day(s) post-birth

TOXIC EFFECTS :

Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight gain) Reproductive - Effects on Newborn - other postnatal measures or effects

REFERENCE :

EESADV Ecotoxicology and Environmental Safety. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1977- Volume(issue)/page/year: 17,291,1989

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

DOSE :

640 mg/kg

SEX/DURATION :

male 64 day(s) pre-mating

TOXIC EFFECTS :

Reproductive - Fertility - male fertility index (e.g. # males impregnating females per # males exposed to fertile nonpregnant females)

REFERENCE :

FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 16,821,1991

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

DOSE :

1280 mg/kg

SEX/DURATION :

male 64 day(s) pre-mating

TOXIC EFFECTS :

Reproductive - Paternal Effects - testes, epididymis, sperm duct

REFERENCE :

FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 16,821,1991

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

DOSE :

1500 mg/kg

SEX/DURATION :

female 13-21 day(s) after conception lactating female 21 day(s) post-birth

TOXIC EFFECTS :

Reproductive - Maternal Effects - other effects Reproductive - Effects on Newborn - weaning or lactation index (e.g., # alive at weaning per # alive at day 4) Reproductive - Effects on Newborn - other postnatal measures or effects

REFERENCE :

AEHLAU Archives of Environmental Health. (Heldref Pub., 4000 Albemarle St., NW, Washington, DC 20016) V.1- 1960- Volume(issue)/page/year: 44,395,1989

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Subcutaneous

DOSE :

4 mg/kg

SEX/DURATION :

female 10 day(s) after conception

TOXIC EFFECTS :

Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Effects on Embryo or Fetus - fetal death Reproductive - Specific Developmental Abnormalities - musculoskeletal system

REFERENCE :

TXCYAC Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85, Limerick, Ireland) V.1- 1973- Volume(issue)/page/year: 79,149,1993

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Subcutaneous

DOSE :

5 mg/kg

SEX/DURATION :

female 6-15 day(s) after conception

TOXIC EFFECTS :

Reproductive - Maternal Effects - other effects Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea) Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)

REFERENCE :

TOLED5 Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977- Volume(issue)/page/year: (Suppl),269,1992