DC4SMe
Modify Date: 2024-04-04 13:18:59
DC4SMe structure
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Common Name | DC4SMe | ||
|---|---|---|---|---|
| CAS Number | 615538-47-1 | Molecular Weight | 764.21 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C35H31ClN5O7PS2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of DC4SMeDC4SMe, a phosphate prodrug of cytotoxic DNA alkylator DC4, can be used in the synthesis of Antibody-drug Conjugate (ADC). DC4SMe exhibits IC50s of 1.9 nM, 2.9 nM, and 1.8 nM for Ramos, Namalwa, and HL60/s cancer cells, respectively. DC4SMe can be used for the targeted treatment of cancer[1]. |
| Name | DC4SMe |
|---|
| Description | DC4SMe, a phosphate prodrug of cytotoxic DNA alkylator DC4, can be used in the synthesis of Antibody-drug Conjugate (ADC). DC4SMe exhibits IC50s of 1.9 nM, 2.9 nM, and 1.8 nM for Ramos, Namalwa, and HL60/s cancer cells, respectively. DC4SMe can be used for the targeted treatment of cancer[1]. |
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| Related Catalog | |
| Target |
Duocarmycins |
| In Vitro | The phosphate prodrug may be a suitable choice for ADCs of effector molecules that do not possess sufficient water solubility or stability[1]. |
| References |
| Molecular Formula | C35H31ClN5O7PS2 |
|---|---|
| Molecular Weight | 764.21 |