615538-47-1
615538-47-1 structure
- Name: DC4SMe
- Chemical Name: DC4SMe
- CAS Number: 615538-47-1
- Molecular Formula: C35H31ClN5O7PS2
- Molecular Weight: 764.21
- Catalog: Signaling Pathways Antibody-drug Conjugate ADC Cytotoxin
- Create Date: 2020-01-23 13:12:51
- Modify Date: 2024-04-04 13:18:59
-
DC4SMe, a phosphate prodrug of cytotoxic DNA alkylator DC4, can be used in the synthesis of Antibody-drug Conjugate (ADC). DC4SMe exhibits IC50s of 1.9 nM, 2.9 nM, and 1.8 nM for Ramos, Namalwa, and HL60/s cancer cells, respectively. DC4SMe can be used for the targeted treatment of cancer[1].
| Name | DC4SMe |
|---|
| Description | DC4SMe, a phosphate prodrug of cytotoxic DNA alkylator DC4, can be used in the synthesis of Antibody-drug Conjugate (ADC). DC4SMe exhibits IC50s of 1.9 nM, 2.9 nM, and 1.8 nM for Ramos, Namalwa, and HL60/s cancer cells, respectively. DC4SMe can be used for the targeted treatment of cancer[1]. |
|---|---|
| Related Catalog | |
| Target |
Duocarmycins |
| In Vitro | The phosphate prodrug may be a suitable choice for ADCs of effector molecules that do not possess sufficient water solubility or stability[1]. |
| References |
| Molecular Formula | C35H31ClN5O7PS2 |
|---|---|
| Molecular Weight | 764.21 |