O-(4-hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine hydrochloride structure
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Common Name | O-(4-hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine hydrochloride | ||
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CAS Number | 6138-47-2 | Molecular Weight | 687.43400 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C15H13ClI3NO4 | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of O-(4-hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine hydrochlorideLiothyronine hydrochloride is an active form of thyroid hormone. Liothyronine hydrochloride is a potent thyroid hormone receptors TRα and TRβ agonist with Kis of 2.33 nM for hTRα and hTRβ, respectively[1][2][3]. |
Name | (2S)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]propanoic acid,hydrochloride |
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Synonym | More Synonyms |
Description | Liothyronine hydrochloride is an active form of thyroid hormone. Liothyronine hydrochloride is a potent thyroid hormone receptors TRα and TRβ agonist with Kis of 2.33 nM for hTRα and hTRβ, respectively[1][2][3]. |
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Related Catalog | |
Target |
Human Endogenous Metabolite |
In Vitro | Liothyronine (T3, 100 nM) hydrochloride stimulates the proliferation of hepatocarcinema cells in which TRβ1 is overexpressed[1]. Liothyronine hydrochloride binds to human β1 thyroid hormone receptor (hTRβ1), and changes its conformation. Liothyronine hydrochloride promotes growth, induces differentiation and regualtes metabolic effects[2]. |
References |
Molecular Formula | C15H13ClI3NO4 |
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Molecular Weight | 687.43400 |
Exact Mass | 686.76700 |
PSA | 92.78000 |
LogP | 5.45500 |
Liothyronine hydrochloride |
trionine |
Liothyronine HCl |
Thyrotradin (TN) |
EINECS 228-120-0 |