Name | (2S)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]propanoic acid,hydrochloride |
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Synonyms |
Liothyronine hydrochloride
trionine Liothyronine HCl Thyrotradin (TN) EINECS 228-120-0 |
Description | Liothyronine hydrochloride is an active form of thyroid hormone. Liothyronine hydrochloride is a potent thyroid hormone receptors TRα and TRβ agonist with Kis of 2.33 nM for hTRα and hTRβ, respectively[1][2][3]. |
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Related Catalog | |
Target |
Human Endogenous Metabolite |
In Vitro | Liothyronine (T3, 100 nM) hydrochloride stimulates the proliferation of hepatocarcinema cells in which TRβ1 is overexpressed[1]. Liothyronine hydrochloride binds to human β1 thyroid hormone receptor (hTRβ1), and changes its conformation. Liothyronine hydrochloride promotes growth, induces differentiation and regualtes metabolic effects[2]. |
References |
Molecular Formula | C15H13ClI3NO4 |
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Molecular Weight | 687.43400 |
Exact Mass | 686.76700 |
PSA | 92.78000 |
LogP | 5.45500 |