Benzo[g]pteridine-2,4(3H,10H)-dione, 10-(2-methoxyethyl)-3-phenyl-

Modify Date: 2025-09-13 22:21:51

Benzo[g]pteridine-2,4(3H,10H)-dione, 10-(2-methoxyethyl)-3-phenyl- Structure
Benzo[g]pteridine-2,4(3H,10H)-dione, 10-(2-methoxyethyl)-3-phenyl- structure
 Common Name Benzo[g]pteridine-2,4(3H,10H)-dione, 10-(2-methoxyethyl)-3-phenyl-
CAS Number 61369-43-5 Molecular Weight 348.36
Density 1.36g/cm3 Boiling Point 508.8ºC at 760 mmHg
Molecular Formula C19H16N4O3 Melting Point N/A
MSDS N/A Flash Point 261.5ºC

 Use of Benzo[g]pteridine-2,4(3H,10H)-dione, 10-(2-methoxyethyl)-3-phenyl-


NSC 288387 is a pan-flavivirus MTase inhibitor. NSC 288387 binds to the SAM-binding pocket. NSC 288387 inhibits ZIKV with an IC50 of 0.2 μM. NSC 288387 also inhibits viral replication in cell culture[1].

 Names

Name 10-(2-methoxyethyl)-3-phenylbenzo[g]pteridine-2,4-dione

  Biological Activity

Description NSC 288387 is a pan-flavivirus MTase inhibitor. NSC 288387 binds to the SAM-binding pocket. NSC 288387 inhibits ZIKV with an IC50 of 0.2 μM. NSC 288387 also inhibits viral replication in cell culture[1].
Related Catalog
References

[1]. Samrat SK, et al. Broad-Spectrum Small-Molecule Inhibitors Targeting the SAM-Binding Site of Flavivirus NS5 Methyltransferase. ACS Infect Dis. 2023 Jul 14;9(7):1319-1333.  

 Chemical & Physical Properties

Density 1.36g/cm3
Boiling Point 508.8ºC at 760 mmHg
Molecular Formula C19H16N4O3
Molecular Weight 348.36
Flash Point 261.5ºC
Exact Mass 348.12200
PSA 79.01000
LogP 1.74200
Index of Refraction 1.682

 Synthetic Route

Benzo[g]pteridine-2,4(3H,10H)-dione, 6,7,8,9-tetrahydro-10-(2-methoxyethyl)-3-phenyl- structure

Benzo[g]pteridi...

CAS#:61369-41-3

~81%

Benzo[g]pteridine-2,4(3H,10H)-dione, 10-(2-methoxyethyl)-3-phenyl- Structure

Benzo[g]pteridi...

CAS#:61369-43-5

Literature: Lacroix, Alain; Schabat, Dominique; Clerin, Daniel; Fleury, Jean-Pierre Bulletin de la Societe Chimique de France, 1987 , # 6 p. 1065 - 1072
Phenylisocyanate structure

Phenylisocyanate

CAS#:103-71-9

~%

Benzo[g]pteridine-2,4(3H,10H)-dione, 10-(2-methoxyethyl)-3-phenyl- Structure

Benzo[g]pteridi...

CAS#:61369-43-5

Literature: Lacroix, Alain; Schabat, Dominique; Clerin, Daniel; Fleury, Jean-Pierre Bulletin de la Societe Chimique de France, 1987 , # 6 p. 1065 - 1072
methyl (3Z)-4-(2-methoxyethyl)-3-(phenylcarbamoylimino)-5,6,7,8-tetrahydroquinoxaline-2-carboxylate structure

methyl (3Z)-4-(...

CAS#:61369-39-9

~%

Benzo[g]pteridine-2,4(3H,10H)-dione, 10-(2-methoxyethyl)-3-phenyl- Structure

Benzo[g]pteridi...

CAS#:61369-43-5

Literature: Lacroix, Alain; Schabat, Dominique; Clerin, Daniel; Fleury, Jean-Pierre Bulletin de la Societe Chimique de France, 1987 , # 6 p. 1065 - 1072
methyl 3-amino-4-(2-methoxyethyl)-7,8-dihydro-6H-quinoxaline-2-carboxylate structure

methyl 3-amino-...

CAS#:61369-37-7

~%

Benzo[g]pteridine-2,4(3H,10H)-dione, 10-(2-methoxyethyl)-3-phenyl- Structure

Benzo[g]pteridi...

CAS#:61369-43-5

Literature: Lacroix, Alain; Schabat, Dominique; Clerin, Daniel; Fleury, Jean-Pierre Bulletin de la Societe Chimique de France, 1987 , # 6 p. 1065 - 1072
3-amino-4-(2-methoxyethyl)-4,6,7,8-tetrahydroquinoxaline-2-carbonitrile structure

3-amino-4-(2-me...

CAS#:107938-86-3

~%

Benzo[g]pteridine-2,4(3H,10H)-dione, 10-(2-methoxyethyl)-3-phenyl- Structure

Benzo[g]pteridi...

CAS#:61369-43-5

Literature: Lacroix, Alain; Schabat, Dominique; Clerin, Daniel; Fleury, Jean-Pierre Bulletin de la Societe Chimique de France, 1987 , # 6 p. 1065 - 1072
(methoxy-2-ethyl)-1-(phenylcarbamoyl)imino-2-hexahydro-1,2,5,6,7,8-quinoxalinecarbonitrile-3 structure

(methoxy-2-ethy...

CAS#:117286-20-1

~%

Benzo[g]pteridine-2,4(3H,10H)-dione, 10-(2-methoxyethyl)-3-phenyl- Structure

Benzo[g]pteridi...

CAS#:61369-43-5

Literature: Lacroix, Alain; Schabat, Dominique; Clerin, Daniel; Fleury, Jean-Pierre Bulletin de la Societe Chimique de France, 1987 , # 6 p. 1065 - 1072
N/A structure

N/A

CAS#:117286-28-9

~29%

Benzo[g]pteridine-2,4(3H,10H)-dione, 10-(2-methoxyethyl)-3-phenyl- Structure

Benzo[g]pteridi...

CAS#:61369-43-5

Literature: Lacroix, Alain; Schabat, Dominique; Clerin, Daniel; Fleury, Jean-Pierre Bulletin de la Societe Chimique de France, 1987 , # 6 p. 1065 - 1072
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Chemsrc provides CAS#:61369-43-5 MSDS, density, melting point, boiling point, structure, etc. Its name is Benzo[g]pteridine-2,4(3H,10H)-dione, 10-(2-methoxyethyl)-3-phenyl->> amp version: Benzo[g]pteridine-2,4(3H,10H)-dione, 10-(2-methoxyethyl)-3-phenyl-

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