A 77-01
Modify Date: 2024-01-04 09:40:11
A 77-01 structure
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Common Name | A 77-01 | ||
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| CAS Number | 607737-87-1 | Molecular Weight | 286.33100 | |
| Density | 1.254g/cm3 | Boiling Point | 481.63ºC at 760 mmHg | |
| Molecular Formula | C18H14N4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 256.391ºC | |
Use of A 77-01A 77-01 is a potent inhibitor of TGF-β type I receptor superfamily activin-like kinase ALK5 with IC50 of 25 nM. IC50 Value: 25 nM [1]Target: ALK5A-77-01 is a close analogue of A-83-01(Axon 1421) and has a very similar biological profile of A-83-01. A-83-01 is found to decompose to A-77-01 under certain circumstances and A-77-01 is likely an active component or metabolite of its prodrug A-83-01. |
| Name | 4-[5-(6-methylpyridin-2-yl)-1H-pyrazol-4-yl]quinoline |
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| Synonym | More Synonyms |
| Description | A 77-01 is a potent inhibitor of TGF-β type I receptor superfamily activin-like kinase ALK5 with IC50 of 25 nM. IC50 Value: 25 nM [1]Target: ALK5A-77-01 is a close analogue of A-83-01(Axon 1421) and has a very similar biological profile of A-83-01. A-83-01 is found to decompose to A-77-01 under certain circumstances and A-77-01 is likely an active component or metabolite of its prodrug A-83-01. |
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| Related Catalog | |
| References |
| Density | 1.254g/cm3 |
|---|---|
| Boiling Point | 481.63ºC at 760 mmHg |
| Molecular Formula | C18H14N4 |
| Molecular Weight | 286.33100 |
| Flash Point | 256.391ºC |
| Exact Mass | 286.12200 |
| PSA | 54.46000 |
| LogP | 3.99530 |
| Index of Refraction | 1.685 |
| Storage condition | 2-8℃ |
| 4-[3-(6-Methyl-2-pyridinyl)-1H-pyrazol-4-yl]-quinolone |
| A 77-01 |