6-Iodoamiloride
Modify Date: 2025-08-26 10:55:42
6-Iodoamiloride structure
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Common Name | 6-Iodoamiloride | ||
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| CAS Number | 60398-23-4 | Molecular Weight | 321.08 | |
| Density | 2.74g/cm3 | Boiling Point | 657.5ºC at 760 mmHg | |
| Molecular Formula | C6H8IN7O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 351.4ºC | |
Use of 6-Iodoamiloride6-Iodoamiloride is a potent acid-sensing ion channel 1 (ASIC1) inhibitor with an IC50 of 88 nM. 6-Iodoamiloride inhibits ASIC3-mediated currents from rat dorsal root ganglion neurons with an IC50 of 230 nM[1]. |
| Name | 3,5-diamino-N-(diaminomethylidene)-6-iodopyrazine-2-carboxamide |
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| Synonym | More Synonyms |
| Description | 6-Iodoamiloride is a potent acid-sensing ion channel 1 (ASIC1) inhibitor with an IC50 of 88 nM. 6-Iodoamiloride inhibits ASIC3-mediated currents from rat dorsal root ganglion neurons with an IC50 of 230 nM[1]. |
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| Related Catalog | |
| Target |
IC50: 88 nM (ASIC1)[1] |
| References |
| Density | 2.74g/cm3 |
|---|---|
| Boiling Point | 657.5ºC at 760 mmHg |
| Molecular Formula | C6H8IN7O |
| Molecular Weight | 321.08 |
| Flash Point | 351.4ºC |
| Exact Mass | 320.98400 |
| PSA | 160.28000 |
| LogP | 1.40610 |
| Index of Refraction | 1.988 |
| InChIKey | FKXYVYMLZGVJIM-UHFFFAOYSA-N |
| SMILES | NC(N)=NC(=O)c1nc(I)c(N)nc1N |
| HS Code | 2934999090 |
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| HS Code | 2934999090 |
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| Summary | 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
| 3,5-diamino-6-iodo-pyrazine-2-carboxylic acid carbamimidoylamide |
| N-Amidino-3,5-diamino-6-iodo-2-pyrazinecarboxamide |
| 6-Iodoamiloride |