Exisulind

Modify Date: 2025-08-27 18:19:49

Exisulind Structure
Exisulind structure
Common Name Exisulind
CAS Number 59973-80-7 Molecular Weight 372.41
Density N/A Boiling Point N/A
Molecular Formula C20H17FO4S Melting Point 248-250ºC
MSDS Chinese Flash Point N/A

 Use of Exisulind


Sulindac sulfone is an mTORC1 pathway inhibitor and a metabolite of Sulindac. Sulindac sulfone inhibits colon cancer cell growth and induces cell cycle arrest. Sulindac sulfone is used in cancer research[1].

 Names

Name sulindac sulfone
Synonym More Synonyms

 Exisulind Biological Activity

Description Sulindac sulfone is an mTORC1 pathway inhibitor and a metabolite of Sulindac. Sulindac sulfone inhibits colon cancer cell growth and induces cell cycle arrest. Sulindac sulfone is used in cancer research[1].
Related Catalog
References

[1]. Aono Y, et al. Sulindac sulfone inhibits the mTORC1 pathway in colon cancer cells by directly targeting voltage-dependent anion channel 1 and 2. Biochem Biophys Res Commun. 2018 Nov 10;505(4):1203-1210.  

 Chemical & Physical Properties

Melting Point 248-250ºC
Molecular Formula C20H17FO4S
Molecular Weight 372.41
Exact Mass 372.08300
PSA 79.82000
LogP 5.11240
InChIKey MVGSNCBCUWPVDA-MFOYZWKCSA-N
SMILES CC1=C(CC(=O)O)c2cc(F)ccc2C1=Cc1ccc(S(C)(=O)=O)cc1
Storage condition -20°C

 Safety Information

RIDADR NONH for all modes of transport
WGK Germany 3

 Precursor & DownStream

Precursor  1

DownStream  0

 Synonyms

2-[(3Z)-6-fluoro-2-methyl-3-[(4-methylsulfonylphenyl)methylidene]inden-1-yl]acetic acid
Sulindac Sulfone
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