Glabrol
Modify Date: 2025-08-25 12:15:17
Glabrol structure
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Common Name | Glabrol | ||
|---|---|---|---|---|
| CAS Number | 59870-65-4 | Molecular Weight | 392.48700 | |
| Density | 1.166g/cm3 | Boiling Point | 600ºC at 760 mmHg | |
| Molecular Formula | C25H28O4 | Melting Point | 121-123 C | |
| MSDS | N/A | Flash Point | 204.3ºC | |
Use of GlabrolGlabrol (Compound 1), One isoprenyl flavonoid was isolated from ethanol extract of licorice roots, is a potent and non-competitive Acyl-coenzyme A: cholesterol acyltransferase (ACAT) inhibitor with an IC50 value of 24.6 μM for rat liver microsomal ACAT activity[1]. |
| Name | 7-hydroxy-2-[4-hydroxy-3-(3-methylbut-2-enyl)phenyl]-8-(3-methylbut-2-enyl)-2,3-dihydrochromen-4-one |
|---|
| Description | Glabrol (Compound 1), One isoprenyl flavonoid was isolated from ethanol extract of licorice roots, is a potent and non-competitive Acyl-coenzyme A: cholesterol acyltransferase (ACAT) inhibitor with an IC50 value of 24.6 μM for rat liver microsomal ACAT activity[1]. |
|---|---|
| Target |
ratACAT:24.6 μM (IC50) |
| In Vitro | Glabrol (Compound 1) decreases cholesteryl ester formation with an IC50 value of 26.0 μM in HepG2 cells[1]. |
| References |
| Density | 1.166g/cm3 |
|---|---|
| Boiling Point | 600ºC at 760 mmHg |
| Melting Point | 121-123 C |
| Molecular Formula | C25H28O4 |
| Molecular Weight | 392.48700 |
| Flash Point | 204.3ºC |
| Exact Mass | 392.19900 |
| PSA | 66.76000 |
| LogP | 5.82170 |
| Index of Refraction | 1.599 |