N-Methylthiourea

Modify Date: 2024-01-07 20:02:12

N-Methylthiourea structure	Common Name	N-Methylthiourea
	CAS Number	598-52-7	Molecular Weight	90.147
	Density	1.1±0.1 g/cm3	Boiling Point	141.1±23.0 °C at 760 mmHg
	Molecular Formula	C₂H₆N₂S	Melting Point	118-121 °C(lit.)
	MSDS	Chinese USA	Flash Point	39.1±22.6 °C
	Symbol	GHS06	Signal Word	Danger

Name	N-Methylthiourea
Synonym	More Synonyms

Density	1.1±0.1 g/cm3
Boiling Point	141.1±23.0 °C at 760 mmHg
Melting Point	118-121 °C(lit.)
Molecular Formula	C₂H₆N₂S
Molecular Weight	90.147
Flash Point	39.1±22.6 °C
Exact Mass	90.025169
PSA	70.14000
LogP	-0.71
Vapour Pressure	6.0±0.3 mmHg at 25°C
Index of Refraction	1.565

N-Methylthiourea MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: YT9000000

CHEMICAL NAME :: Urea, 1-methyl-2-thio-

CAS REGISTRY NUMBER :: 598-52-7

LAST UPDATED :: 199709

DATA ITEMS CITED :: 9

MOLECULAR FORMULA :: C2-H6-N2-S

MOLECULAR WEIGHT :: 90.16

WISWESSER LINE NOTATION :: SUYZM1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 50 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 90,260,1947

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1850 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: THERAP Therapie. (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris, France) V.1- 1946- Volume(issue)/page/year: 35,409,1980

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: TJADAB Teratology, The International Journal of Abnormal Development. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968- Volume(issue)/page/year: 23,335,1981

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >2885 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: YKKZAJ Yakugaku Zasshi. Journal of Pharmacy. (Nippon Yakugakkai, 2-12-15 Shibuya, Shibuya-ku, Tokyo 150, Japan) No.1- 1881- Volume(issue)/page/year: 94,1419,1974 ** REPRODUCTIVE DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 500 mg/kg

SEX/DURATION :: female 12 day(s) after conception

TOXIC EFFECTS :: Reproductive - Specific Developmental Abnormalities - eye/ear Reproductive - Specific Developmental Abnormalities - craniofacial (including nose and tongue) Reproductive - Specific Developmental Abnormalities - gastrointestinal system

REFERENCE :: TJADAB Teratology, The International Journal of Abnormal Development. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968- Volume(issue)/page/year: 23,335,1981

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 200 mg/kg

SEX/DURATION :: female 14 day(s) after conception

TOXIC EFFECTS :: Reproductive - Specific Developmental Abnormalities - Central Nervous System Reproductive - Specific Developmental Abnormalities - musculoskeletal system Reproductive - Specific Developmental Abnormalities - urogenital system

REFERENCE :: TJADAB Teratology, The International Journal of Abnormal Development. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968- Volume(issue)/page/year: 26(1),19A,1982

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 250 mg/kg

SEX/DURATION :: female 14 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)

REFERENCE :: TJADAB Teratology, The International Journal of Abnormal Development. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968- Volume(issue)/page/year: 23,335,1981

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 400 mg/kg

SEX/DURATION :: female 10 day(s) after conception

TOXIC EFFECTS :: Reproductive - Specific Developmental Abnormalities - urogenital system

REFERENCE :: TJADAB Teratology, The International Journal of Abnormal Development. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968- Volume(issue)/page/year: 28,38A,1983

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 1 gm/kg

SEX/DURATION :: female 10 day(s) after conception

TOXIC EFFECTS :: Reproductive - Specific Developmental Abnormalities - musculoskeletal system

REFERENCE :: 49WEAZ "Pesticide Chemistry: Human Welfare and the Environment, Proceedings of the International Congress of Pesticide Chemistry, 5th, Kyoto, Japan, 1982," Miyamoto, J. and Kearney, P.C., eds., Oxford, UK, Pergamon Press Ltd., 1983 Volume(issue)/page/year: 3,479,1983

Symbol	GHS06
Signal Word	Danger
Hazard Statements	H300
Precautionary Statements	P264-P301 + P310
Personal Protective Equipment	Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
Hazard Codes	T:Toxic;
Risk Phrases	R25
Safety Phrases	S36/37/39-S45
RIDADR	UN 2811 6.1/PG 2
WGK Germany	3
RTECS	YT9000000
Packaging Group	II
Hazard Class	6.1
HS Code	2930909090

Precursor 10
CAS#:556-61-6 Methyl isothioc... CAS#:37929-27-4 USAF K-1338 CAS#:27406-60-6 6-hydroxy-1,4,4... CAS#:75039-91-7 ethyl 3-(N-meth...
CAS#:13037-11-1 Carbamodithioic... CAS#:52664-26-3 ethyl N-methylc... CAS#:38475-06-8 N,N''-dimethyl-... CAS#:16486-25-2 N-(methylcarbam...
CAS#:625-57-0 O-Ethyl thiocar... CAS#:74-89-5 methylamine
DownStream 9
CAS#:463-56-9 thiocyanic acid CAS#:7664-41-7 Ammonia CAS#:74-89-5 methylamine CAS#:108249-21-4 amino(methylimi...
CAS#:5422-44-6 1-Methyl-1H-tet... CAS#:41306-45-0 1,2-Dimethyliso... CAS#:25433-05-0 3,4,5-trimethyl... CAS#:2933-32-6 4(5H)-Thiazolon...
CAS#:598-50-5 1-Methylurea

HS Code	2930909090
Summary	2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

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MFCD00004938

EINECS 209-936-6

Thiourea, N-methyl-

1-Methylthiourea

methylthiourea