11R-VIVIT

Modify Date: 2024-01-11 15:18:29

11R-VIVIT Structure
11R-VIVIT structure
Common Name 11R-VIVIT
CAS Number 592517-80-1 Molecular Weight 3573.15
Density N/A Boiling Point N/A
Molecular Formula C147H259N67O36S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 11R-VIVIT


11R-VIVIT is a potent NFAT inhibitor. 11R-VIVIT inhibits LPS or LPS plus IFN-γ-induced IL-12 p40, IL-12 p70, IL-23 and TNF secretion from bone marrow-derived macrophages (BMDMs). 11R-VIVIT also attenuates NO production and Nos2 mRNA expression in LPS-stimulated BMDMs. 11R-VIVIT improves symptoms in a mouse model of colitis. Exhibits immunosuppressive effects; enhances graft survival in mice.

 Names

Name 11R-VIVIT

 11R-VIVIT Biological Activity

Description 11R-VIVIT is a potent NFAT inhibitor. 11R-VIVIT inhibits LPS or LPS plus IFN-γ-induced IL-12 p40, IL-12 p70, IL-23 and TNF secretion from bone marrow-derived macrophages (BMDMs). 11R-VIVIT also attenuates NO production and Nos2 mRNA expression in LPS-stimulated BMDMs. 11R-VIVIT improves symptoms in a mouse model of colitis. Exhibits immunosuppressive effects; enhances graft survival in mice.
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 Chemical & Physical Properties

Molecular Formula C147H259N67O36S
Molecular Weight 3573.15
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