11R-VIVIT

Names

[ Name ]:
11R-VIVIT

Biological Activity

[Description]:

11R-VIVIT is a potent NFAT inhibitor. 11R-VIVIT inhibits LPS or LPS plus IFN-γ-induced IL-12 p40, IL-12 p70, IL-23 and TNF secretion from bone marrow-derived macrophages (BMDMs). 11R-VIVIT also attenuates NO production and Nos2 mRNA expression in LPS-stimulated BMDMs. 11R-VIVIT improves symptoms in a mouse model of colitis. Exhibits immunosuppressive effects; enhances graft survival in mice.

[Related Catalog]:

Signaling Pathways >> Others >> Others

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₄₇H₂₅₉N₆₇O₃₆S

[ Molecular Weight ]:
3573.15

Related Compounds

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