3-Fluoro-4-hydroxypropiophenone

Modify Date: 2024-01-04 19:14:11

3-Fluoro-4-hydroxypropiophenone Structure
3-Fluoro-4-hydroxypropiophenone structure
Common Name 3-Fluoro-4-hydroxypropiophenone
CAS Number 586-16-3 Molecular Weight 168.16500
Density 1.2g/cm3 Boiling Point 288.5ºC at 760 mmHg
Molecular Formula C9H9FO2 Melting Point N/A
MSDS N/A Flash Point 128.3ºC

 Names

Name 1-(3-Fluoro-4-hydroxyphenyl)-1-propanone
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.2g/cm3
Boiling Point 288.5ºC at 760 mmHg
Molecular Formula C9H9FO2
Molecular Weight 168.16500
Flash Point 128.3ºC
Exact Mass 168.05900
PSA 37.30000
LogP 2.12400
Index of Refraction 1.522

 Synthetic Route

~67%

3-Fluoro-4-hydroxypropiophenone Structure

3-Fluoro-4-hydr...

CAS#:586-16-3

Literature: CENTAURUS BIOPHARMA CO., LTD.; XIAO, Dengming; ZHU, Li; HU, Yuandong; YU, Rong; HU, Wei; ZHAO, Na; PENG, Yong; LUO, Hong; HAN, Yongxin Patent: WO2013/97773 A1, 2013 ; Location in patent: Paragraph 0168 ;

~9%

3-Fluoro-4-hydroxypropiophenone Structure

3-Fluoro-4-hydr...

CAS#:586-16-3

Literature: Pfizer Inc. Patent: US6258827 B1, 2001 ; US 6258827 B1 Title/Abstract Full Text Show Details Pfizer Inc. Patent: US6046213 A1, 2000 ;

~%

3-Fluoro-4-hydroxypropiophenone Structure

3-Fluoro-4-hydr...

CAS#:586-16-3

Literature: SCHERING AKTIENGESELLSCHAFT Patent: WO2006/27236 A1, 2006 ; Location in patent: Page/Page column 49-51 ;

~%

3-Fluoro-4-hydroxypropiophenone Structure

3-Fluoro-4-hydr...

CAS#:586-16-3

Literature: CENTAURUS BIOPHARMA CO., LTD.; XIAO, Dengming; ZHU, Li; HU, Yuandong; YU, Rong; HU, Wei; ZHAO, Na; PENG, Yong; LUO, Hong; HAN, Yongxin Patent: WO2013/97773 A1, 2013 ;

~%

3-Fluoro-4-hydroxypropiophenone Structure

3-Fluoro-4-hydr...

CAS#:586-16-3

Literature: CENTAURUS BIOPHARMA CO., LTD.; XIAO, Dengming; ZHU, Li; HU, Yuandong; YU, Rong; HU, Wei; ZHAO, Na; PENG, Yong; LUO, Hong; HAN, Yongxin Patent: WO2013/97773 A1, 2013 ;

~%

3-Fluoro-4-hydroxypropiophenone Structure

3-Fluoro-4-hydr...

CAS#:586-16-3

Literature: Buu-Hoi et al. Journal of Organic Chemistry, 1953 , vol. 18, p. 910,914

 Synonyms

1-(3-Fluor-4-hydroxy-phenyl)-propan-1-on
1-(3-fluoro-2-pyridinyl)piperazine hydrogen maleate
Piperazine,1-(3-fluoro-2-pyridinyl)-,(2Z)-2-butenedioate (1:1)
4-propionyl-2-fluorophenol
1-(3-fluoro-4-hydroxy-phenyl)-propan-1-one
L 644 maleate