l-azatyrosine

Modify Date: 2024-01-03 00:02:40

l-azatyrosine structure	Common Name	l-azatyrosine
	CAS Number	58525-82-9	Molecular Weight	182.17700
	Density	1.324g/cm3	Boiling Point	358.2ºC at 760mmHg
	Molecular Formula	C₈H₁₀N₂O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	170.4ºC

Use of l-azatyrosine

L-Azatyrosine is an antitumor antibiotic isolated from Streptomyces chibaensis. L-Azatyrosine can restore normal phenotypic behavior to transformed cells bearing oncogenic Ras genes[1][2].

Name	l-azatyrosine
Synonym	More Synonyms

Description	L-Azatyrosine is an antitumor antibiotic isolated from Streptomyces chibaensis. L-Azatyrosine can restore normal phenotypic behavior to transformed cells bearing oncogenic Ras genes[1][2].
Related Catalog	Research Areas >> Cancer Research Areas >> Infection
References	[1]. Adamczyk M, et, al. Enantioselective synthesis of (2-pyridyl)alanines via catalytic hydrogenation and application to the synthesis of L-azatyrosine. Org Lett. 2001 Oct 4;3(20):3157-9. [2]. Shindo-Okada N, et, al. Permanent conversion of mouse and human cells transformed by activated ras or raf genes to apparently normal cells by treatment with the antibiotic azatyrosine. Mol Carcinog. 1989;2(3):159-67.

Description

L-Azatyrosine is an antitumor antibiotic isolated from Streptomyces chibaensis. L-Azatyrosine can restore normal phenotypic behavior to transformed cells bearing oncogenic Ras genes[1][2].

Related Catalog

Research Areas >> Cancer

Research Areas >> Infection

References

[1]. Adamczyk M, et, al. Enantioselective synthesis of (2-pyridyl)alanines via catalytic hydrogenation and application to the synthesis of L-azatyrosine. Org Lett. 2001 Oct 4;3(20):3157-9.

[2]. Shindo-Okada N, et, al. Permanent conversion of mouse and human cells transformed by activated ras or raf genes to apparently normal cells by treatment with the antibiotic azatyrosine. Mol Carcinog. 1989;2(3):159-67.

Density	1.324g/cm3
Boiling Point	358.2ºC at 760mmHg
Molecular Formula	C₈H₁₀N₂O₃
Molecular Weight	182.17700
Flash Point	170.4ºC
Exact Mass	182.06900
PSA	96.44000
LogP	0.44190
Index of Refraction	1.602

Precursor 6
CAS#:59781-08-7 5-(Benzyloxy)-2... CAS#:372520-55-3 (S)-methyl 2-((... CAS#:1121-78-4 6-Methyl-3-pyridinol CAS#:142-08-5 2-pyridone
CAS#:127-17-3 Pyruvic acid CAS#:31181-78-9 2-Pyridinemetha...
DownStream 0