24, 25-Dihydroxy VD2

Modify Date: 2024-01-04 20:27:41

24, 25-Dihydroxy VD2 structure	Common Name	24, 25-Dihydroxy VD2
	CAS Number	58050-55-8	Molecular Weight	428.64700
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₈H₄₄O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of 24, 25-Dihydroxy VD2

24, 25-Dihydroxy VD2 is a hydroxylated metabolite of Vitamin D2; a synthetic analog of Vitamin D.

Name	(E,6R)-6-[(1R,3aS,4E,7aR)-4-[(2Z)-2-[(5S)-5-hydroxy-2-methylidenecyclohexylidene]ethylidene]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-1-yl]-2,3-dimethylhept-4-ene-2,3-diol
Synonym	More Synonyms

Description	24, 25-Dihydroxy VD2 is a hydroxylated metabolite of Vitamin D2; a synthetic analog of Vitamin D.
Related Catalog	Signaling Pathways >> Vitamin D Related >> VD/VDR Research Areas >> Metabolic Disease
References	[1]. McGraw CA, Hug G. Simultaneous measurement of 25-hydroxy, 24,25-dihydroxy-, and 1,25-dihydroxyvitamin D without use of HPLC. Med Lab Sci. 1990 Jan;47(1):17-25. [2]. Katsumi K, Okano T, Ono Y, Maegaki E, Nishimura K, Baba M, Kobayashi T, Miyata O, Naito T, Ninomiya I. Syntheses of 24,25-dihydroxyvitamin D2, 24,25-dihydroxy-22-dehydrovitamin D3, 25-hydroxy-24-oxo-22-dehydrovitamin D3 and 22,24,25-trihydroxyvitamin D3. [3]. Horst RL, Littledike ET, Gray RW, Napoli JL. Impaired 24,25-dihydroxyvitamin D production in anephric human and pig. J Clin Invest. 1981 Jan;67(1):274-80. [4]. Glenville Jones2, Heinrich K. Schnoes, Leon Levan et al.Isolation and identification of 24-hydroxyvitamin D2 and 24,25-dihydroxyvitamin D2. Archives of Biochemistry and Biophysics.Volume 202, Issue 2, July 1980, Pages 450-457 [5]. Glenville Jones, Alan Rosenthal,David Segev et al. Isolation and identification of 24,25-dihydroxy vitamin D2 by use of the perfused rat kidney. Biochemistry, 1979, 18 (6), pp 1094-1101

Description

24, 25-Dihydroxy VD2 is a hydroxylated metabolite of Vitamin D2; a synthetic analog of Vitamin D.

Related Catalog

Signaling Pathways >> Vitamin D Related >> VD/VDR

Research Areas >> Metabolic Disease

References

[1]. McGraw CA, Hug G. Simultaneous measurement of 25-hydroxy, 24,25-dihydroxy-, and 1,25-dihydroxyvitamin D without use of HPLC. Med Lab Sci. 1990 Jan;47(1):17-25.

[2]. Katsumi K, Okano T, Ono Y, Maegaki E, Nishimura K, Baba M, Kobayashi T, Miyata O, Naito T, Ninomiya I. Syntheses of 24,25-dihydroxyvitamin D2, 24,25-dihydroxy-22-dehydrovitamin D3, 25-hydroxy-24-oxo-22-dehydrovitamin D3 and 22,24,25-trihydroxyvitamin D3.

[3]. Horst RL, Littledike ET, Gray RW, Napoli JL. Impaired 24,25-dihydroxyvitamin D production in anephric human and pig. J Clin Invest. 1981 Jan;67(1):274-80.

[4]. Glenville Jones2, Heinrich K. Schnoes, Leon Levan et al.Isolation and identification of 24-hydroxyvitamin D2 and 24,25-dihydroxyvitamin D2. Archives of Biochemistry and Biophysics.Volume 202, Issue 2, July 1980, Pages 450-457

[5]. Glenville Jones, Alan Rosenthal,David Segev et al. Isolation and identification of 24,25-dihydroxy vitamin D2 by use of the perfused rat kidney. Biochemistry, 1979, 18 (6), pp 1094-1101

Molecular Formula	C₂₈H₄₄O₃
Molecular Weight	428.64700
Exact Mass	428.32900
PSA	60.69000
LogP	5.87080
Storage condition	2-8℃

3-Methyl-3-[(te...

CAS#:60283-66-1

24, 25-Dihydroxy VD2

CAS#:58050-55-8

Literature: Chemical and Pharmaceutical Bulletin, , vol. 32, # 9 p. 3744 - 3746

N/A

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24, 25-Dihydroxy VD2

CAS#:58050-55-8

Literature: Chemical and Pharmaceutical Bulletin, , vol. 32, # 9 p. 3744 - 3746

(22E)-3β,24,25-...

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24, 25-Dihydroxy VD2

CAS#:58050-55-8

Literature: Chemical and Pharmaceutical Bulletin, , vol. 32, # 9 p. 3744 - 3746

3-acetoxy-2'-ph...

CAS#:28421-57-0

24, 25-Dihydroxy VD2

CAS#:58050-55-8

Literature: Chemical and Pharmaceutical Bulletin, , vol. 32, # 9 p. 3744 - 3746

3-acetoxy-2'-ph...

CAS#:28421-56-9

24, 25-Dihydroxy VD2

CAS#:58050-55-8

Literature: Chemical and Pharmaceutical Bulletin, , vol. 32, # 9 p. 3744 - 3746

3β-acetoxy-22,2...

CAS#:107717-75-9

24, 25-Dihydroxy VD2

CAS#:58050-55-8

Literature: Chemical and Pharmaceutical Bulletin, , vol. 35, # 3 p. 970 - 979

N/A

CAS#:95511-44-7

24, 25-Dihydroxy VD2

CAS#:58050-55-8

Literature: Chemical and Pharmaceutical Bulletin, , vol. 32, # 9 p. 3744 - 3746

(24R,S)-ergosta...

CAS#:95586-93-9

24, 25-Dihydroxy VD2

CAS#:58050-55-8

Literature: Chemical and Pharmaceutical Bulletin, , vol. 35, # 3 p. 970 - 979

Precursor 4
CAS#:60283-66-1 3-Methyl-3-[(te... CAS#:28421-57-0 3-acetoxy-2'-ph... CAS#:28421-56-9 3-acetoxy-2'-ph... CAS#:107717-75-9 3β-acetoxy-22,2...
DownStream 0

(4E,6R)-2,3-Dimethyl-6-[(1R,3aS,4E,7aR)-octahydro-4-[(2Z)-2-[(5S)-5-hydroxy-2-methylenecyclohexylidene]ethylidene]-7a-methyl-1H-inden-1-yl]-4-heptene-2,3-diol

24,25-Dihydroxy VD2

24,25-Dihydroxy Vitamin D2

(3|A,5Z,7E,22E,24|I)-9,10-Secoergosta-5,7,10(19),22-tetraene-3,24,25-triol

(24R)-24,25-dihydroxyvitamin D2

24(S),25-dihydroxyvitamin D2

CS-0802

24, 25-Dihydroxy VD2

24, 25-Dihydroxy VD2

Use of 24, 25-Dihydroxy VD2

Names

24, 25-Dihydroxy VD2 Biological Activity

Chemical & Physical Properties

Synthetic Route

Precursor & DownStream

Synonyms