mannomustine

Modify Date: 2024-01-16 01:05:37

mannomustine structure	Common Name	mannomustine
	CAS Number	576-68-1	Molecular Weight	305.19900
	Density	1.353g/cm3	Boiling Point	541.9ºC at 760 mmHg
	Molecular Formula	C₁₀H₂₂Cl₂N₂O₄	Melting Point	278°C (rough estimate)
	MSDS	N/A	Flash Point	281.5ºC

Name	(2R,3R,4R,5R)-1,6-bis(2-chloroethylamino)hexane-2,3,4,5-tetrol
Synonym	More Synonyms

Density	1.353g/cm3
Boiling Point	541.9ºC at 760 mmHg
Melting Point	278°C (rough estimate)
Molecular Formula	C₁₀H₂₂Cl₂N₂O₄
Molecular Weight	305.19900
Flash Point	281.5ºC
Exact Mass	304.09600
PSA	104.98000
Index of Refraction	1.544

CHEMICAL IDENTIFICATION

RTECS NUMBER :: OP2100000

CHEMICAL NAME :: Mannitol, 1,6-bis((2-chloroethyl)amino)-1,6-dideoxy-, D-,

CAS REGISTRY NUMBER :: 576-68-1

LAST UPDATED :: 199707

DATA ITEMS CITED :: 13

MOLECULAR FORMULA :: C10-H22-Cl2-N2-O4

MOLECULAR WEIGHT :: 305.24

WISWESSER LINE NOTATION :: G2M1YQYQYQYQ1M2G -D

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 56 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 56 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 90 mg/kg

TOXIC EFFECTS :: Nutritional and Gross Metabolic - weight loss or decreased weight gain

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 90 mg/kg

TOXIC EFFECTS :: Tumorigenic - protects against induction of experimental tumors

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 50 mg/kg

TOXIC EFFECTS :: Blood - changes in spleen Tumorigenic - protects against induction of experimental tumors

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 50 mg/kg

TOXIC EFFECTS :: Blood - leukopenia

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 20 mg/kg

TOXIC EFFECTS :: Blood - changes in spleen Tumorigenic - protects against induction of experimental tumors

TYPE OF TEST :: Cytogenetic analysis

TYPE OF TEST :: Sister chromatid exchange

MUTATION DATA

TYPE OF TEST :: Sister chromatid exchange

TEST SYSTEM :: Rodent - hamster Cells - not otherwise specified

DOSE/DURATION :: 2900 nmol/L

REFERENCE :: SOGEBZ Soviet Genetics. English translation of GNKAA5. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) V.2- 1966- Volume(issue)/page/year: 18,210,1982

1,6-bis-aziridi...

CAS#:16658-08-5

mannomustine

CAS#:576-68-1

Literature: Vargha et al. Journal of the Chemical Society, 1957 , p. 805,809

1,6-bis-(2-hydr...

CAS#:108991-70-4

mannomustine

CAS#:576-68-1

Literature: Vargha et al. Journal of the Chemical Society, 1957 , p. 805,809

2,7-bis[(4-meth...

CAS#:7465-84-1

mannomustine

CAS#:576-68-1

Literature: Vargha et al. Journal of the Chemical Society, 1957 , p. 805,809

Precursor 3
CAS#:16658-08-5 1,6-bis-aziridi... CAS#:108991-70-4 1,6-bis-(2-hydr... CAS#:7465-84-1 2,7-bis[(4-meth...
DownStream 0

Mannit-lost [German]

Mannomustin

Mannitol nitrogen mustard

Manomustina [INN-Spanish]

Mannomustine [INN:BAN:DCF]

Mannit-mustard [German]

Mannit-Lost

Mannomustinum [INN-Latin]

1,6-Bis-<(2-chlorethyl)-amino>-1,6-dideoxy-D-mannitol

1,6-Bis-(2-chlor-aethylamino)-1,6-didesoxy-D-mannit

BCM (cytostatic)

mannomustine

1,6-bis-(2-chloro-ethylamino)-1,6-dideoxy-D-mannitol

1,6-Bis-<2-chlor-ethylamino>-1,6-didesoxy-D-mannit

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: mannomustine
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

Get all suppliers and price by the below link:

mannomustine suppliers

mannomustine price

mannomustine

Names

Chemical & Physical Properties

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

Synthetic Route

Precursor & DownStream

Synonyms