5-Chloro-2-fluorobenzonitrile

Modify Date: 2025-09-11 19:19:57

5-Chloro-2-fluorobenzonitrile structure	Common Name	5-Chloro-2-fluorobenzonitrile
	CAS Number	57381-34-7	Molecular Weight	155.557
	Density	1.3±0.1 g/cm3	Boiling Point	202.5±20.0 °C at 760 mmHg
	Molecular Formula	C₇H₃ClFN	Melting Point	67-70°C
	MSDS	Chinese USA	Flash Point	76.3±21.8 °C
	Symbol	GHS07	Signal Word	Warning

Name	5-Chloro-2-fluorobenzonitrile
Synonym	More Synonyms

Density	1.3±0.1 g/cm3
Boiling Point	202.5±20.0 °C at 760 mmHg
Melting Point	67-70°C
Molecular Formula	C₇H₃ClFN
Molecular Weight	155.557
Flash Point	76.3±21.8 °C
Exact Mass	154.993805
PSA	23.79000
LogP	2.15
Vapour Pressure	0.3±0.4 mmHg at 25°C
Index of Refraction	1.537

5-Chloro-2-fluorobenzonitrile MSDS(Chinese)

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302-H312-H332
Precautionary Statements	P280
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi:Irritant;
Risk Phrases	R20/21/22
Safety Phrases	S26-S36
RIDADR	3439
Packaging Group	III
Hazard Class	6.1
HS Code	2926909090

5-Chloro-2-nitr...

CAS#:34662-31-2

~93%

5-Chloro-2-fluo...

CAS#:57381-34-7

Literature: Clark, James H.; Nightingale, David J. Journal of Fluorine Chemistry, 1996 , vol. 78, # 1 p. 91 - 93

Precursor 1
CAS#:34662-31-2 5-Chloro-2-nitr...
DownStream 2
CAS#:674793-32-9 5-chloro-2-fluo... CAS#:5685-72-3 5-Chloro-1H-ind...

HS Code	2926909090
Summary	HS:2926909090 other nitrile-function compounds VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Microwave-assisted synthesis of 3-aminobenzo[b]thiophene scaffolds for the preparation of kinase inhibitors.

.PubMed ID

Microwave irradiation of 2-halobenzonitriles and methyl thioglycolate in the presence of triethylamine in DMSO at 130 °C provides rapid access to 3-aminobenzo[b]thiophenes in 58-96% yield. This transf...

Analysis of Small Molecule X-Ray Crystal Structures: Chemical Crystallography with Undergraduate Students in a Teaching Laboratory. Aldeborgh H, et al.

J. Chem. Crystallogr. 44(2) , 70-81, (2014)

5-Chloro-2-fluorobenzonitrile

NCR CG FF

5-Chloro-2-fluorobenzonitirle

Benzonitrile, 5-chloro-2-fluoro-

MFCD01631434

EINECS 260-710-3