Drazoxolon

Modify Date: 2025-08-25 11:31:51

Drazoxolon Structure
Drazoxolon structure
 Common Name Drazoxolon
CAS Number 5707-69-7 Molecular Weight 237.64200
Density 1.45g/cm3 Boiling Point 321.8ºC at 760 mmHg
Molecular Formula C10H8ClN3O2 Melting Point 167ºC
MSDS USA Flash Point >100 °C
Symbol GHS06 GHS09
GHS06, GHS09		 Signal Word Danger

 Use of Drazoxolon


Drazoxolon is a lipid-soluble fungicide.

 Names

Name drazoxolon
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.45g/cm3
Boiling Point 321.8ºC at 760 mmHg
Melting Point 167ºC
Molecular Formula C10H8ClN3O2
Molecular Weight 237.64200
Flash Point >100 °C
Exact Mass 237.03100
PSA 63.05000
LogP 1.54920
Index of Refraction 1.648

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
NY2800000
CHEMICAL NAME :
4,5-Isoxazoledione, 3-methyl-, 4-((o-chlorophenyl)hydrazone)
CAS REGISTRY NUMBER :
5707-69-7
LAST UPDATED :
199204
DATA ITEMS CITED :
10
MOLECULAR FORMULA :
C10-H8-Cl-N3-O2
MOLECULAR WEIGHT :
237.66
WISWESSER LINE NOTATION :
T5NOVYJ DUNMR BG& E1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
126 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 7,481,1969
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
20 mg/kg
TOXIC EFFECTS :
Brain and Coverings - recordings from specific areas of CNS Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - other changes
REFERENCE :
FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 7,481,1969
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
129 mg/kg
TOXIC EFFECTS :
Brain and Coverings - recordings from specific areas of CNS Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - other changes
REFERENCE :
FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 7,481,1969
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
20 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 7,481,1969
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Mammal - cat
DOSE/DURATION :
50 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 7,481,1969
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
100 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 7,481,1969
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
20 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 7,481,1969
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
12500 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 7,481,1969
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Bird - pigeon
DOSE/DURATION :
12 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 7,481,1969
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Bird - chicken
DOSE/DURATION :
100 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 7,481,1969

 Safety Information

Symbol GHS06 GHS09
GHS06, GHS09
Signal Word Danger
Hazard Statements H301-H410
Precautionary Statements P273-P301 + P310-P501
Personal Protective Equipment Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
Hazard Codes T,N
Risk Phrases 25-50/53
Safety Phrases 22-24-36/37-45-60-61
RIDADR 2588
WGK Germany 3
RTECS NY2800000
Packaging Group III
Hazard Class 6.1(b)

 Synthetic Route

ethyl 2-[(2-chlorophenyl)diazenyl]-3-oxobutanoate structure

ethyl 2-[(2-chl...

CAS#:33165-52-5

~35%

Drazoxolon Structure

Drazoxolon

CAS#:5707-69-7

Literature: Tanaka; Matsuo; Nakanishi; Jo; Shiota; Yamaguchi; Yoshino; Kawaguchi Chemical and Pharmaceutical Bulletin, 1984 , vol. 32, # 8 p. 3291 - 3298
2-Chloroaniline structure

2-Chloroaniline

CAS#:95-51-2

~%

Drazoxolon Structure

Drazoxolon

CAS#:5707-69-7

Literature: Chemical and Pharmaceutical Bulletin, , vol. 32, # 8 p. 3291 - 3298

 Precursor & DownStream

Precursor  2

DownStream  0

 Synonyms

Drazoxolone
(EZ)-4-(2-chlorophenylhydrazono)-3-methylisoxazol-5(4H)-one
Caswell No. 207C
(EZ)-4-(2-chlorophenylhydrazono)-3-methyl-1,2-oxazol-5(4H)-one
(4Z)-4-[(2-chlorophenyl)hydrazinylidene]-3-methyl-1,2-oxazol-5-one
Ganocide
MFCD00144225
Sopracol 781
Saisan
EINECS 227-197-8
Sopracol
Mil-col
(4Ξ)-4-[(2-chlorophenyl)hydrazinylidene]-3-methyl-1,2-oxazol-5(4H)-one
DRAZOXOLON
3-methyl-4,5-isoxazoledione 4-[(2-chlorophenyl)hydrazone]
PP781
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Chemsrc provides Drazoxolon(CAS#:5707-69-7) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of Drazoxolon are included as well.>> amp version: Drazoxolon

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