8-Hydroxy-2'-deoxyguanosine-15N5

Modify Date: 2024-04-05 18:17:54

8-Hydroxy-2'-deoxyguanosine-15N5 structure	Common Name	8-Hydroxy-2'-deoxyguanosine-15N5
	CAS Number	569649-11-2	Molecular Weight	288.21
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₀H₁₃₁₅N₅O₅	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of 8-Hydroxy-2'-deoxyguanosine-15N5

8-Hydroxy-2'-deoxyguanosine-15N5 is the 15N labeled 8-Hydroxy-2'-deoxyguanosine[1]. 8-Hydroxy-2'-deoxyguanosine is a critical biomarker of oxidative stress and carcinogenesis[2].

Name	8-Hydroxy-2'-deoxyguanosine-15N5

Description	8-Hydroxy-2'-deoxyguanosine-15N5 is the 15N labeled 8-Hydroxy-2'-deoxyguanosine[1]. 8-Hydroxy-2'-deoxyguanosine is a critical biomarker of oxidative stress and carcinogenesis[2].
Related Catalog	Research Areas >> Cancer
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Valavanidis A, et al. 8-hydroxy-2' -deoxyguanosine (8-OHdG): A critical biomarker of oxidative stress and carcinogenesis. J Environ Sci Health C Environ Carcinog Ecotoxicol Rev. 2009 Apr;27(2):120-39.

Molecular Formula	C₁₀H₁₃₁₅N₅O₅
Molecular Weight	288.21