Cyclo(Pro-Leu)

Modify Date: 2024-01-08 17:14:33

Cyclo(Pro-Leu) Structure
Cyclo(Pro-Leu) structure
Common Name Cyclo(Pro-Leu)
CAS Number 5654-86-4 Molecular Weight 210.27
Density N/A Boiling Point N/A
Molecular Formula C11H18N2O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Cyclo(Pro-Leu)


Cyclo(Pro-Leu) (A 65190) is an active metabolite. Cyclo(Pro-Leu) can be isolated from Streptomyces sp. BM8. Cyclo(Pro-Leu) can be used for the research of cancer[1].

 Names

Name 3-Isobutyl-2,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione

 Cyclo(Pro-Leu) Biological Activity

Description Cyclo(Pro-Leu) (A 65190) is an active metabolite. Cyclo(Pro-Leu) can be isolated from Streptomyces sp. BM8. Cyclo(Pro-Leu) can be used for the research of cancer[1].
Related Catalog
Target

Microbial Metabolite

In Vitro Cyclo(Pro-Leu) (compound 7) (1.23 μg/mL-300 μg/mL; 48 h) has cytotoxic activity for HT-29, MCF-7, A375, K562, and NCM460 cell lines with IC50 values of 101.56 μM, 78.78 μM, 51.13 μM, 21.72 μM and 775.86 μM, respectively[1].
References

[1]. Shengsheng Lu, et al. Secondary Metabolites with Cytotoxic Activities from Streptomyces sp. BM-8 Isolated from the Feces of Equusquagga. Molecules. 2021 Dec 13;26(24):7556.  

 Chemical & Physical Properties

Molecular Formula C11H18N2O2
Molecular Weight 210.27
Storage condition -20°C
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