Bromonitromethane

Modify Date: 2024-01-02 09:02:14

Bromonitromethane structure	Common Name	Bromonitromethane
	CAS Number	563-70-2	Molecular Weight	139.93600
	Density	2.07	Boiling Point	146-148 °C (750 mmHg)
	Molecular Formula	CH₂BrNO₂	Melting Point	N/A
	MSDS	Chinese USA	Flash Point	4°C
	Symbol	GHS03, GHS07	Signal Word	Danger

Use of Bromonitromethane

Bromonitromethane is a halonitromethane that can be used in production of various protected α-bromo nitroalkane donors for use in Umpolung Amide Synthesis (UmAS)[1][2].

Name	Bromonitromethane
Synonym	More Synonyms

Description	Bromonitromethane is a halonitromethane that can be used in production of various protected α-bromo nitroalkane donors for use in Umpolung Amide Synthesis (UmAS)[1][2].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
References	[1]. Dawn M Makley, et al. Silyl Imine Electrophiles in Enantioselective Catalysis: A Rosetta Stone for Peptide Homologation, Enabling Diverse N-protected Aryl Glycines From Aldehydes in Three Steps. Org Lett. 2014 Jun 6;16(11):3146-9. [2]. Alicia Marsà, et al. In Vitro Studies on the Tumorigenic Potential of the Halonitromethanes Trichloronitromethane and Bromonitromethane. Toxicol In Vitro. 2017 Dec;45(Pt 1):72-80.

Description

Bromonitromethane is a halonitromethane that can be used in production of various protected α-bromo nitroalkane donors for use in Umpolung Amide Synthesis (UmAS)[1][2].

Related Catalog

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

References

[1]. Dawn M Makley, et al. Silyl Imine Electrophiles in Enantioselective Catalysis: A Rosetta Stone for Peptide Homologation, Enabling Diverse N-protected Aryl Glycines From Aldehydes in Three Steps. Org Lett. 2014 Jun 6;16(11):3146-9.

[2]. Alicia Marsà, et al. In Vitro Studies on the Tumorigenic Potential of the Halonitromethanes Trichloronitromethane and Bromonitromethane. Toxicol In Vitro. 2017 Dec;45(Pt 1):72-80.

Density	2.07
Boiling Point	146-148 °C (750 mmHg)
Molecular Formula	CH₂BrNO₂
Molecular Weight	139.93600
Flash Point	4°C
Exact Mass	138.92700
PSA	45.82000
LogP	1.13870
Index of Refraction	1.485-1.495

Bromonitromethane MSDS(Chinese)

Symbol	GHS03, GHS07
Signal Word	Danger
Hazard Statements	H272-H315-H319-H335
Precautionary Statements	P220-P261-P305 + P351 + P338
Personal Protective Equipment	Eyeshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard Codes	O: Oxidizing agent;Xn: Harmful;
Risk Phrases	R8;R36/37/38
Safety Phrases	S36/37/39-S26-S17-S36
RIDADR	3098
RTECS	PA5360000
Packaging Group	III
Hazard Class	5.1
HS Code	2904909090

HS Code	2904909090
Summary	HS:2904909090 sulphonated, nitrated or nitrosated derivatives of hydrocarbons, whether or not halogenated VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

Silyl imine electrophiles in enantioselective catalysis: a Rosetta Stone for peptide homologation, enabling diverse N-protected aryl glycines from aldehydes in three steps.

Org. Lett. , (2014)

We report that N-(trimethylsilyl)imines serve in the Bis(AMidine)-catalyzed addition of bromonitromethane with a high degree of enantioselection. This allows for the production of a range of protected...

Stereoselective synthesis of highly functionalized nitrocyclopropanes through the organocatalyic Michael-addition-initiated cyclization of bromonitromethane and β,γ-unsaturated α-ketoesters.

Chem. Asian J. 8(11) , 2859-63, (2013)

A highly diastereo- and enantioselective cyclopropanation of β,γ-unsaturated α-ketoesters with bromonitromethane has been successfully developed through a domino Michael-addition/intramolecular-alkyla...

Synthesis of enantiopure 2-C-glycosyl-3-nitrochromenes.

J. Org. Chem. 78(24) , 12831-6, (2013)

A novel methodology has been developed to obtain enantiopure 2-C-glycosyl-3-nitrochromenes. First, (Z)-1-bromo-1-nitroalkenes were prepared from the corresponding sugar aldehydes through a sodium iodi...

MFCD00007401

EINECS 209-258-0

bromo(nitro)methane