Dihydrodeoxyuridine

Modify Date: 2024-01-11 04:04:09

Dihydrodeoxyuridine Structure
Dihydrodeoxyuridine structure
Common Name Dihydrodeoxyuridine
CAS Number 5626-99-3 Molecular Weight 230.22
Density 1.31g/cm3 Boiling Point 481.1ºC at 760mmHg
Molecular Formula C9H14N2O5 Melting Point N/A
MSDS Chinese USA Flash Point 244.7ºC

 Use of Dihydrodeoxyuridine


Dihydrodeoxyuridine (H2dUrd) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 5,6-dihydrodeoxyuridine
Synonym More Synonyms

 Dihydrodeoxyuridine Biological Activity

Description Dihydrodeoxyuridine (H2dUrd) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Density 1.31g/cm3
Boiling Point 481.1ºC at 760mmHg
Molecular Formula C9H14N2O5
Molecular Weight 230.22
Flash Point 244.7ºC
Exact Mass 230.09000
PSA 99.10000
Index of Refraction 1.638
Storage condition -20°C

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport
HS Code 2934999090

 Precursor & DownStream

Precursor  1

DownStream  1

 Customs

HS Code 2934999090
Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles1

More Articles
Oxytocin reverses amphetamine-induced deficits in social bonding: evidence for an interaction with nucleus accumbens dopamine.

J. Neurosci. 34(25) , 8499-506, (2014)

Drug addiction has devastating consequences on social behaviors and can lead to the impairment of social bonding. Accumulating evidence indicates that alterations in oxytocin (OT) and dopamine (DA) ne...

 Synonyms

2'-deoxy-5,6-dihydrouridine
Tetrahydrodeoxyuridine
5,6-dihydro-2'-deoxyuridine
L-2'-deoxy-5,6-dihydrouridine
tetrahydro-2'-deoxyuridine
Dihydrodeoxyuridine