2,4-Dichloroaniline

Modify Date: 2025-08-21 17:13:03

2,4-Dichloroaniline Structure
2,4-Dichloroaniline structure
 Common Name 2,4-Dichloroaniline
CAS Number 554-00-7 Molecular Weight 162.017
Density 1.4±0.1 g/cm3 Boiling Point 242.1±20.0 °C at 760 mmHg
Molecular Formula C6H5Cl2N Melting Point 59-62 °C(lit.)
MSDS Chinese USA Flash Point 100.2±21.8 °C
Symbol GHS06 GHS08 GHS09
GHS06, GHS08, GHS09		 Signal Word Danger

 Names

Name 2,4-dichloroaniline
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 242.1±20.0 °C at 760 mmHg
Melting Point 59-62 °C(lit.)
Molecular Formula C6H5Cl2N
Molecular Weight 162.017
Flash Point 100.2±21.8 °C
Exact Mass 160.979904
PSA 26.02000
LogP 2.74
Vapour Pressure 0.0±0.5 mmHg at 25°C
Index of Refraction 1.614
Water Solubility Insoluble,

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
BX2600000
CHEMICAL NAME :
Aniline, 2,4-dichloro-
CAS REGISTRY NUMBER :
554-00-7
BEILSTEIN REFERENCE NO. :
0386422
LAST UPDATED :
199710
DATA ITEMS CITED :
10
MOLECULAR FORMULA :
C6-H5-Cl2-N
MOLECULAR WEIGHT :
162.02
WISWESSER LINE NOTATION :
ZR BG DG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1600 mg/kg
TOXIC EFFECTS :
Behavioral - muscle weakness Lungs, Thorax, or Respiration - cyanosis Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
TSCAT* Office of Toxic Substances Report. (U.S. Environmental Protection Agency, Office of Toxic Substances, 401 M St., SW, Washington, DC 20460) Volume(issue)/page/year: OTS 206512
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
400 mg/kg
TOXIC EFFECTS :
Behavioral - muscle weakness Lungs, Thorax, or Respiration - cyanosis Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
TSCAT* Office of Toxic Substances Report. (U.S. Environmental Protection Agency, Office of Toxic Substances, 401 M St., SW, Washington, DC 20460) Volume(issue)/page/year: OTS 206512
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
400 mg/kg
TOXIC EFFECTS :
Behavioral - muscle weakness Lungs, Thorax, or Respiration - cyanosis Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
TSCAT* Office of Toxic Substances Report. (U.S. Environmental Protection Agency, Office of Toxic Substances, 401 M St., SW, Washington, DC 20460) Volume(issue)/page/year: OTS 206512
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
400 mg/kg
TOXIC EFFECTS :
Behavioral - muscle weakness Lungs, Thorax, or Respiration - cyanosis Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
TSCAT* Office of Toxic Substances Report. (U.S. Environmental Protection Agency, Office of Toxic Substances, 401 M St., SW, Washington, DC 20460) Volume(issue)/page/year: OTS 206512
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - cat
DOSE/DURATION :
113 mg/kg
TOXIC EFFECTS :
Behavioral - hallucinations, distorted perceptions Lungs, Thorax, or Respiration - cyanosis Blood - methemoglobinemia-carboxyhemoglobin
REFERENCE :
AEXPBL Archiv fuer Experimentelle Pathologie und Pharmakologie. (Leipzig, Ger. Dem. Rep.) V.1-109, 1873-1925. For publisher information, see NSAPCC. Volume(issue)/page/year: 72,241,1913

 Safety Information

Symbol GHS06 GHS08 GHS09
GHS06, GHS08, GHS09
Signal Word Danger
Hazard Statements H301-H311-H331-H373-H410
Precautionary Statements P261-P273-P280-P301 + P310-P311-P501
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
Hazard Codes T:Toxic;N:Dangerousfortheenvironment;
Risk Phrases R23/24/25;R33;R50/53
Safety Phrases S28-S36/37-S45-S60-S61-S28A
RIDADR UN 3442 6.1/PG 2
WGK Germany 3
RTECS BX2600000
Packaging Group II
Hazard Class 6.1
HS Code 2921499090

 Customs

HS Code 2921420090
Summary HS:2921420090 aniline derivatives and their salts VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

 Articles26

More Articles
Biodegradation of 2-chloroaniline, 3-chloroaniline, and 4-chloroaniline by a novel strain Delftia tsuruhatensis H1.

J. Hazard. Mater. 179(1-3) , 875-82, (2010)

A new strain Delftia tsuruhatensis H1 able to degrade several chloroanilines (CAs) as individual compounds or a mixture was isolated from a CA-degrading mixed bacterial culture. The isolated strain co...

Sensitivity of muscle satellite cells to pollutants: an in vitro and in vivo comparative approach.

Aquat. Toxicol. 53(3-4) , 247-63, (2001)

Muscle satellite cells from rainbow trout were exposed in vitro to increasing concentrations of different xenobiotics: copper, dichloroaniline, prochloraz, nonyl-phenol polyethexylate. Mortality and p...

Expression of delayed cell death (DCD) in the progeny of fish cells surviving 2,4-dichloroaniline (2,4-DCA) exposure.

Aquat. Toxicol. 63(3) , 207-19, (2003)

Interest in and concern for the quality of the environment has prompted a great deal of research into methods of measuring and assessing changes in it. One problem of major interest is that of increas...

 Synonyms

2,4-Dichloroaniline
2,4-di-Cl-aniline
2,4-Dichloro Aniline
Benzenamine, 2,4-dichloro-
1-Amino-2,4-dichlorobenzene
2,4-Dichloranilin
2,4-dichloro
EINECS 209-057-8
2,4-DCA
AURORA KA-688
2,4-dichloro-anilin
1,5-dichloro-4-aminobenzene
o,p-Dichloroaniline
2,4-dichloro-aniline
4-Dichloroaniline
MFCD00007661
aniline, 2,4-dichloro-
2,4-dichloro-phenylamine
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