Propoxycaine (hydrochloride)

Modify Date: 2025-08-25 18:09:48

Propoxycaine (hydrochloride) structure	Common Name	Propoxycaine (hydrochloride)
	CAS Number	550-83-4	Molecular Weight	330.85000
	Density	N/A	Boiling Point	434.4ºC at 760mmHg
	Molecular Formula	C₁₆H₂₇ClN₂O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	216.5ºC

Use of Propoxycaine (hydrochloride)

Propoxycaine hydrochloride is the hydrochloride salt form of Propoxycaine, a para-aminobenzoic acid ester with local anesthetic activity.Target: sodium channelPropoxycaine binds to and inhibits voltage-gated sodium channels, thereby inhibiting the ionic flux required for the initiation and conduction of impulses. This results in a loss of sensation.

Name	2-(diethylamino)ethyl 4-amino-2-propoxybenzoate,hydrochloride
Synonym	More Synonyms

Description	Propoxycaine hydrochloride is the hydrochloride salt form of Propoxycaine, a para-aminobenzoic acid ester with local anesthetic activity.Target: sodium channelPropoxycaine binds to and inhibits voltage-gated sodium channels, thereby inhibiting the ionic flux required for the initiation and conduction of impulses. This results in a loss of sensation.
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> Sodium Channel Research Areas >> Neurological Disease

Boiling Point	434.4ºC at 760mmHg
Molecular Formula	C₁₆H₂₇ClN₂O₃
Molecular Weight	330.85000
Flash Point	216.5ºC
Exact Mass	330.17100
PSA	64.79000
LogP	3.93940
Storage condition	2-8℃

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DG3066000

CHEMICAL NAME :: Benzoic acid, 4-amino-2-propoxy-, 2-(diethylamino)ethyl ester, monohydrochloride

CAS REGISTRY NUMBER :: 550-83-4

LAST UPDATED :: 199709

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C16-H26-N2-O3.Cl-H

MOLECULAR WEIGHT :: 330.90

WISWESSER LINE NOTATION :: 3OR CZ FVO2N2&2 &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 80 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: APFRAD Annales Pharmaceutiques Francaises. (SPPIF, B.P.22, F-41353 Vineuil, France) V.1- 1943- Volume(issue)/page/year: 40,133,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 7417 ug/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Vascular - BP lowering not characterized in autonomic section Lungs, Thorax, or Respiration - other changes

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 123,269,1958

RIDADR	UN 2811 6.1 / PGIII

Pravocaine hydrochloride

EINECS 208-988-7

WIN 3459

Propoxycaine HCl

Ravocaine hydrochloride

Blockain

4-Amino-2-propoxybenzoic acid 2-(diethylamino)ethyl ester hydrochloride

BENZOIC ACID,4-AMINO-2-PROPOXY-,2-(DIETHYLAMINO)ETHYL ESTER,MONOHYDROCHLORIDE

Propoxycaine Hyrochloride

Propoxycaine hydrochloride

Propoxycaine (hydrochloride)

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Propoxycaine (hydrochloride)

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