1H-Naphtho(2,3-d)-1,2,3-triazole-4,9-dione, 1-phenyl-

Modify Date: 2024-01-11 17:12:35

1H-Naphtho(2,3-d)-1,2,3-triazole-4,9-dione, 1-phenyl- Structure
1H-Naphtho(2,3-d)-1,2,3-triazole-4,9-dione, 1-phenyl- structure
Common Name 1H-Naphtho(2,3-d)-1,2,3-triazole-4,9-dione, 1-phenyl-
CAS Number 5466-47-7 Molecular Weight 275.26
Density 1.44g/cm3 Boiling Point 523.4ºC at 760 mmHg
Molecular Formula C16H9N3O2 Melting Point N/A
MSDS N/A Flash Point 270.3ºC

 Use of 1H-Naphtho(2,3-d)-1,2,3-triazole-4,9-dione, 1-phenyl-


IDO1/TDO-IN-2 (Compound 1) is a potent inhibitor of IDO1/TDO with IC50s of 0.1 and 0.07 μM. IDO1/TDO-IN-2 has the potential for the research of cancer diseases[1].

 Names

Name 3-phenylbenzo[f]benzotriazole-4,9-dione

 Chemical & Physical Properties

Density 1.44g/cm3
Boiling Point 523.4ºC at 760 mmHg
Molecular Formula C16H9N3O2
Molecular Weight 275.26
Flash Point 270.3ºC
Exact Mass 275.06900
PSA 64.85000
LogP 2.04270
Index of Refraction 1.75

 Safety Information

HS Code 2933990090

 Synthetic Route

~26%

1H-Naphtho(2,3-d)-1,2,3-triazole-4,9-dione, 1-phenyl- Structure

1H-Naphtho(2,3-...

CAS#:5466-47-7

Literature: Shrestha, Jaya P.; Fosso, Marina Y.; Bearss, Jeremiah; Chang, Cheng-Wei Tom European Journal of Medicinal Chemistry, 2014 , vol. 77, p. 96 - 102

~23%

1H-Naphtho(2,3-d)-1,2,3-triazole-4,9-dione, 1-phenyl- Structure

1H-Naphtho(2,3-...

CAS#:5466-47-7

Literature: Zhang, Qian; Shrestha, Jaya P.; Chang, Cheng-Wei Tom Tetrahedron Letters, 2014 , vol. 55, # 10 p. 1839 - 1842

~%

1H-Naphtho(2,3-d)-1,2,3-triazole-4,9-dione, 1-phenyl- Structure

1H-Naphtho(2,3-...

CAS#:5466-47-7

Literature: Zhang, Qian; Shrestha, Jaya P.; Chang, Cheng-Wei Tom Tetrahedron Letters, 2014 , vol. 55, # 10 p. 1839 - 1842

~%

1H-Naphtho(2,3-d)-1,2,3-triazole-4,9-dione, 1-phenyl- Structure

1H-Naphtho(2,3-...

CAS#:5466-47-7

Literature: Fries; Billig Chemische Berichte, 1925 , vol. 58, p. 1133

~%

1H-Naphtho(2,3-d)-1,2,3-triazole-4,9-dione, 1-phenyl- Structure

1H-Naphtho(2,3-...

CAS#:5466-47-7

Literature: Fries; Billig Chemische Berichte, 1925 , vol. 58, p. 1133

~%

1H-Naphtho(2,3-d)-1,2,3-triazole-4,9-dione, 1-phenyl- Structure

1H-Naphtho(2,3-...

CAS#:5466-47-7

Literature: Fries; Billig Chemische Berichte, 1925 , vol. 58, p. 1133

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
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