Isogosferol
Modify Date: 2024-01-10 09:46:31
Isogosferol structure
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Common Name | Isogosferol | ||
|---|---|---|---|---|
| CAS Number | 53319-52-1 | Molecular Weight | 286.279 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 498.2±45.0 °C at 760 mmHg | |
| Molecular Formula | C16H14O5 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 255.1±28.7 °C | |
Use of IsogosferolIsogosferol ((+)-Isogospherol; Isogospherol) is a potent anti-inflammatory agent. Isogosferol decreases LPS (HY-D1056)-stimulated NO and IL-1β expression. Isogosferol decreases the LPS (HY-D1056)-stimulated expression of iNOS, COX-2, NF-κB, and pERK1/2[1]. |
| Name | 9-(2-hydroxy-3-methylbut-3-enoxy)furo[3,2-g]chromen-7-one |
|---|---|
| Synonym | More Synonyms |
| Description | Isogosferol ((+)-Isogospherol; Isogospherol) is a potent anti-inflammatory agent. Isogosferol decreases LPS (HY-D1056)-stimulated NO and IL-1β expression. Isogosferol decreases the LPS (HY-D1056)-stimulated expression of iNOS, COX-2, NF-κB, and pERK1/2[1]. |
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| Related Catalog | |
| In Vitro | Isogosferol (100, 200 µM; 1+16 h) 降低 RAW 264.7 细胞中 LPS (HY-D1056) 刺激的 NO 表达[1]。 Isogosferol (0, 25, 50, 100, 200 µM; 1+16 h) 以剂量依赖性方式降低 LPS 刺激的 iNOS、COX-2 蛋白表达[1]。 Isogosferol (0, 25, 50, 100, 200 µM; 1+1 h) 以剂量依赖性方式降低 LPS 刺激的 NF-κB 和 pERK1/2 表达[1]。 Isogosferol (50, 100, 200 µM µM; 1+16 h) 减少 LPS 刺激的促炎细胞因子 IL-1β 的释放[1]。 Cell Viability Assay[1] Cell Line: RAW 264.7 cells Concentration: 100, 200 µM (stimulated with LPS (1 µg/mL)) Incubation Time: 1+16 Result: Remarkably down-regulated the LPS-stimulated NO expression with an IC50 of 148 μM and shows no effect on cell viability. Western Blot Analysis[1] Cell Line: 0, 25, 50, 100, 200 µM Concentration: 1+16 Incubation Time: 1+16 Result: Decreased the expression of iNOS, COX-2 protein in a dose-dependent manner. |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 498.2±45.0 °C at 760 mmHg |
| Molecular Formula | C16H14O5 |
| Molecular Weight | 286.279 |
| Flash Point | 255.1±28.7 °C |
| Exact Mass | 286.084137 |
| PSA | 72.81000 |
| LogP | 2.33 |
| Vapour Pressure | 0.0±1.3 mmHg at 25°C |
| Index of Refraction | 1.620 |
| Hazard Codes | Xi |
|---|
| 9-[(2-Hydroxy-3-methyl-3-buten-1-yl)oxy]-7H-furo[3,2-g]chromen-7-one |
| 9-((2-Hydroxy-3-methyl-3-butenyl)oxy)-7H-furo(3,2-g)(1)benzopyran-7-one |
| rtuprhihxsawdp-uhfffaoysa |
| 7H-Furo[3,2-g][1]benzopyran-7-one, 9-[[(2S)-2-hydroxy-3-methyl-3-buten-1-yl]oxy]- |
| 9-[(2-Hydroxy-3-methylbut-3-en-1-yl)oxy]-7H-furo[3,2-g]chromen-7-one |
| 9-{[(2S)-2-Hydroxy-3-methyl-3-buten-1-yl]oxy}-7H-furo[3,2-g]chromen-7-one |
| 7H-Furo(3,2-g)(1)benzopyran-7-one, 9-((2-hydroxy-3-methyl-3-butenyl)oxy)- |
| 7H-Furo[3,2-g][1]benzopyran-7-one, 9-[(2-hydroxy-3-methyl-3-buten-1-yl)oxy]- |
- BioBioPha
- China
- Product Name: Isogosferol
- Price: ￥3400.0/5mg
- Purity: 98.0%
- Stocking Period: 1 Day
- Contact: Xueping-Zheng
- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: Isogosferol
- Price: ￥3438.0/5mg
- Purity: 98.0%
- Stocking Period: 2 Day
- Contact: Liu jia
- DC Chemicals Limited
- China
- Product Name: Isogosferol
- Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Tony Cao
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: ISOGOSFEROL
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Ms Wang
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