N-(2-Hydroxyethyl)oxamic acid

Modify Date: 2024-01-02 18:27:01

N-(2-Hydroxyethyl)oxamic acid Structure
N-(2-Hydroxyethyl)oxamic acid structure
Common Name N-(2-Hydroxyethyl)oxamic acid
CAS Number 5270-73-5 Molecular Weight 133.10300
Density 1.436g/cm3 Boiling Point N/A
Molecular Formula C4H7NO4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of N-(2-Hydroxyethyl)oxamic acid


N-(2-hydroxyethyl)-oxamic acid is formed when Metronidazole is reduced either chemically or by the action of the intestinal bacteria. Metronidazole, a nitroimidazole antibiotic, has activity against various protozoans and most Gram-negative and Gram-positive anaerobic bacteria[1][2].

 Names

Name 2-(2-hydroxyethylamino)-2-oxoacetic acid
Synonym More Synonyms

 N-(2-Hydroxyethyl)oxamic acid Biological Activity

Description N-(2-hydroxyethyl)-oxamic acid is formed when Metronidazole is reduced either chemically or by the action of the intestinal bacteria. Metronidazole, a nitroimidazole antibiotic, has activity against various protozoans and most Gram-negative and Gram-positive anaerobic bacteria[1][2].
Related Catalog
References

[1]. Koch RL, et al. The anaerobic metabolism of metronidazole forms N-(2-hydroxyethyl)-oxamic acid. J Pharmacol Exp Ther. 1979;208(3):406-410.

[2]. Freeman CD, et al. Metronidazole. A therapeutic review and update. Drugs. 1997;54(5):679-708.

 Chemical & Physical Properties

Density 1.436g/cm3
Molecular Formula C4H7NO4
Molecular Weight 133.10300
Exact Mass 133.03800
PSA 86.63000
Index of Refraction 1.501

 Safety Information

HS Code 2924199090

 Customs

HS Code 2924199090
Summary 2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Synonyms

Hydroxyethyloxamic acid
N-(2-Hydroxyethyl)oxamic acid
[(2-hydroxyethyl)amino](oxo)acetic acid