N-(2-Hydroxyethyl)oxamic acid

Names

[ Name ]:
N-(2-Hydroxyethyl)oxamic acid

[Synonym ]:
Hydroxyethyloxamic acid
N-(2-Hydroxyethyl)oxamic acid
[(2-hydroxyethyl)amino](oxo)acetic acid

Biological Activity

[Description]:

N-(2-hydroxyethyl)-oxamic acid is formed when Metronidazole is reduced either chemically or by the action of the intestinal bacteria. Metronidazole, a nitroimidazole antibiotic, has activity against various protozoans and most Gram-negative and Gram-positive anaerobic bacteria[1][2].

[Related Catalog]:

Research Areas >> Infection

[References]

[1]. Koch RL, et al. The anaerobic metabolism of metronidazole forms N-(2-hydroxyethyl)-oxamic acid. J Pharmacol Exp Ther. 1979;208(3):406-410.

[2]. Freeman CD, et al. Metronidazole. A therapeutic review and update. Drugs. 1997;54(5):679-708.

Chemical & Physical Properties

[ Density]:
1.436g/cm3

[ Molecular Formula ]:
C₄H₇NO₄

[ Molecular Weight ]:
133.10300

[ Exact Mass ]:
133.03800

[ PSA ]:
86.63000

[ Index of Refraction ]:
1.501

Safety Information

[ HS Code ]:
2924199090

Customs

[ HS Code ]: 2924199090

[ Summary ]:
2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Related Compounds

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