Angiotensin II (1-4), human

Modify Date: 2024-01-14 17:47:31

Angiotensin II (1-4), human Structure
Angiotensin II (1-4), human structure
Common Name Angiotensin II (1-4), human
CAS Number 52580-29-7 Molecular Weight 551.59
Density N/A Boiling Point N/A
Molecular Formula C24H37N7O8 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Angiotensin II (1-4), human


Angiotensin II (1-4), human is an endogenous peptide produced from AT I by angiotensin-converting-enzyme (ACE). Angiotensin II binds the AT II type 1 (AT1) receptor, stimulating GPCRs in vascular smooth muscle cells and increasing intracellular Ca2+ levels. Angiotensin II also acts at the Na+/H+ exchanger in the proximal tubules of the kidney[1][2].

 Names

Name Angiotensin II (1-4), human

 Angiotensin II (1-4), human Biological Activity

Description Angiotensin II (1-4), human is an endogenous peptide produced from AT I by angiotensin-converting-enzyme (ACE). Angiotensin II binds the AT II type 1 (AT1) receptor, stimulating GPCRs in vascular smooth muscle cells and increasing intracellular Ca2+ levels. Angiotensin II also acts at the Na+/H+ exchanger in the proximal tubules of the kidney[1][2].
Related Catalog
References

[1]. De Giusti VC, et al. Modulation of the cardiac sodium/bicarbonate cotransporter by the renin angiotensin aldosterone system: pathophysiological consequences. Front Physiol. 2014 Jan 17;4:411.

[2]. Moon JY, et al. Recent Update of Renin-angiotensin-aldosterone System in the Pathogenesis of Hypertension. Electrolyte Blood Press. 2013 Dec;11(2):41-5.

 Chemical & Physical Properties

Molecular Formula C24H37N7O8
Molecular Weight 551.59