Angiotensin II (1-4), human

Modify Date: 2025-08-25 10:23:39

Angiotensin II (1-4), human structure	Common Name	Angiotensin II (1-4), human
	CAS Number	52580-29-7	Molecular Weight	551.59
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₄H₃₇N₇O₈	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Angiotensin II (1-4), human

Angiotensin II (1-4), human is an endogenous peptide produced from AT I by angiotensin-converting-enzyme (ACE). Angiotensin II binds the AT II type 1 (AT1) receptor, stimulating GPCRs in vascular smooth muscle cells and increasing intracellular Ca2+ levels. Angiotensin II also acts at the Na+/H+ exchanger in the proximal tubules of the kidney[1][2].

Name	Angiotensin II (1-4), human

Description	Angiotensin II (1-4), human is an endogenous peptide produced from AT I by angiotensin-converting-enzyme (ACE). Angiotensin II binds the AT II type 1 (AT1) receptor, stimulating GPCRs in vascular smooth muscle cells and increasing intracellular Ca2+ levels. Angiotensin II also acts at the Na+/H+ exchanger in the proximal tubules of the kidney[1][2].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Angiotensin Receptor Research Areas >> Metabolic Disease
References	[1]. De Giusti VC, et al. Modulation of the cardiac sodium/bicarbonate cotransporter by the renin angiotensin aldosterone system: pathophysiological consequences. Front Physiol. 2014 Jan 17;4:411. [2]. Moon JY, et al. Recent Update of Renin-angiotensin-aldosterone System in the Pathogenesis of Hypertension. Electrolyte Blood Press. 2013 Dec;11(2):41-5.

Description

Related Catalog

Signaling Pathways >> GPCR/G Protein >> Angiotensin Receptor

Research Areas >> Metabolic Disease

References

[1]. De Giusti VC, et al. Modulation of the cardiac sodium/bicarbonate cotransporter by the renin angiotensin aldosterone system: pathophysiological consequences. Front Physiol. 2014 Jan 17;4:411.

[2]. Moon JY, et al. Recent Update of Renin-angiotensin-aldosterone System in the Pathogenesis of Hypertension. Electrolyte Blood Press. 2013 Dec;11(2):41-5.

Molecular Formula	C₂₄H₃₇N₇O₈
Molecular Weight	551.59
InChIKey	COIOSOPVFHACOV-UHFFFAOYSA-N
SMILES	CC(C)C1C2=C(NCCN1C(=O)C1CCCCC1)C(C)(C)N(Cc1ccccc1)C2=O.CC1(C)C2=C(C(=O)N1Cc1ccccc1)C(c1ccco1)N(C(=O)C1CCCC1)CCN2.CC1(C)C2=C(C(=O)N1Cc1ccccc1)C(c1ccco1)N(C(=O)Cc1ccccc1)CCN2.CC1(C)C2=C(C(=O)N1Cc1ccccc1)C(c1ccco1)N(C(=O)c1ccc3c(c1)OCO3)CCN2.CC1(C)C2=C(C(=O)N1Cc1ccccc1)C(c1ccco1)N(C(=O)c1ccccc1)CCN2.CC1(C)C2=C(C(=O)N1Cc1ccccc1)C(c1ccco1)N(C(=O)c1ccccc1)CCN2.Cc1ccc(C(=O)N2CCNC3=C(C(=O)N(Cc4ccccc4)C3(C)C)C2c2ccco2)cc1

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Angiotensin II (1-4), human

Use of Angiotensin II (1-4), human

Names

Angiotensin II (1-4), human Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.