Vitamin E Nicotinate
Modify Date: 2024-01-04 10:28:45
Vitamin E Nicotinate structure
|
Common Name | Vitamin E Nicotinate | ||
|---|---|---|---|---|
| CAS Number | 51898-34-1 | Molecular Weight | 535.800 | |
| Density | 1.0±0.1 g/cm3 | Boiling Point | 649.0±55.0 °C at 760 mmHg | |
| Molecular Formula | C35H53NO3 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 346.3±31.5 °C | |
Use of Vitamin E Nicotinate(±)-α-Tocopherol nicotinate, vitamin E - nicotinate, is an orally active fat-soluble antioxidant that prevents lipid peroxidation in cell membranes. (±)-α-Tocopherol nicotinate is hydrolysed in the blood to α -tocopherol and niacin and may be used in studies of related vascular diseases[1][2]. |
| Name | (±)-α-Tocopherol nicotinate |
|---|---|
| Synonym | More Synonyms |
| Description | (±)-α-Tocopherol nicotinate, vitamin E - nicotinate, is an orally active fat-soluble antioxidant that prevents lipid peroxidation in cell membranes. (±)-α-Tocopherol nicotinate is hydrolysed in the blood to α -tocopherol and niacin and may be used in studies of related vascular diseases[1][2]. |
|---|---|
| Related Catalog | |
| In Vitro | (±)-α-Tocopherol nicotinate can help slow the progression of microangiopathy in type 2 diabetics by reducing lipid peroxidation stress in the red blood cell membrane, improving blood rheology and red blood cell deformability[1]. (±)-α-Tocopherol nicotinate (Vitamin E) (2 μg/mL, 24 h) increases the proportion of CD4+CD8-T cells in thymocytes by pretreating the thymic epithelial cell line IT45-R1 and then incubating it with immature T cells[2]. |
| In Vivo | (±)-α-Tocopherol nicotinate (Vitamin E) (in animal feedings, 50 mg/kg or 585 mg/kg, 7 weeks) significantly increases the proportion of CD4+CD8- T cells and the expression of ICAM-1 in thymic epithelial cells (TECs) isolated of male Fisher rats at high dose concentrations of 585 mg/kg compared to low dose treatment of 50 mg/kg[2]. |
| References |
| Density | 1.0±0.1 g/cm3 |
|---|---|
| Boiling Point | 649.0±55.0 °C at 760 mmHg |
| Molecular Formula | C35H53NO3 |
| Molecular Weight | 535.800 |
| Flash Point | 346.3±31.5 °C |
| Exact Mass | 535.402527 |
| PSA | 48.42000 |
| LogP | 13.23 |
| Vapour Pressure | 0.0±1.9 mmHg at 25°C |
| Index of Refraction | 1.514 |
| Storage condition | 2-8°C |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
|
Antiarrhythmic activity of alpha-tocopherol nicotinate and related compounds and their physico-chemical properties.
Arzneimittelforschung 37(8) , 920-3, (1987) The effect of alpha-tocopherol nicotinate (Renascin), alpha-tocopherol and dodecanoic acid (lauric acid) on the positive inotropic action of ouabain and digoxin and on cardiac glycoside induced arrhyt... |
|
|
High-performance liquid chromatographic determination of alpha-tocopheryl nicotinate in cosmetic preparations.
J. Chromatogr. A. 593(1-2) , 95-7, (1992) alpha-Tocopheryl nicotinate (alpha-TN) accelerates blood circulation and stimulates hair follicle cells, hence it is an active ingredient in a broad range of cosmetic products. A reversed-phase high-p... |
|
|
Comparisons between absorption of vitamin E in patients with chronic pancreatitis and healthy controls: the bioavailability of vitamin E.
Tohoku J. Exp. Med. 148(4) , 393-401, (1986) The fasting serum levels of alpha-tocopherol were determined by high-pressure liquid chromatography in 13 patients with chronic pancreatitis of whom 7 were positive for pancreatic calcification (CCP) ... |
| MFCD00057302 |
| (2R)-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydro-2H-chromen-6-yl pyridine-3-carboxylate |
| Vitamin E nicotinate |
| UNII:QCP2FMP7I8 |
| EINECS 257-501-4 |
| (2R)-2,5,7,8-Tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydro-2H-chromen-6-yl nicotinate |
| [2R-2R*(4R*,8R*)]-3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-ol nicotinate |
| 3-Pyridinecarboxylic acid, (2R)-3,4-dihydro-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-2H-1-benzopyran-6-yl ester |
- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: Vitamin E Nicotinate
- Price: ￥328.0/100mg
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Liu jia
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: Vitamin E Nicotinate
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Ms Wang
Get all suppliers and price by the below link: