Dehydroglyasperin D

Modify Date: 2025-08-22 10:01:27

Dehydroglyasperin D structure	Common Name	Dehydroglyasperin D
	CAS Number	517885-72-2	Molecular Weight	368.42
	Density	1.2±0.1 g/cm3	Boiling Point	557.9±50.0 °C at 760 mmHg
	Molecular Formula	C₂₂H₂₄O₅	Melting Point	N/A
	MSDS	N/A	Flash Point	291.2±30.1 °C

Use of Dehydroglyasperin D

Dehydroglyasperin D inhibits rat and human Aldose Reductase (AR) (IC50: 62.4 μM and 176.2 μM respectively). Dehydroglyasperin D has anti-obesity, antioxidant effects. Dehydroglyasperin D shows anti-inflammatory activity by inhibiting COX-2 expression and the MLK3 signaling pathway. Dehydroglyasperin D also inhibits melanin synthesis. Dehydroglyasperin D is a prenylated flavonoid that can be isolated from Glycyrrhiza uralensi[1][2][3].

Name	4-(5,7-dimethoxy-6-(3-methylbut-2-en-1-yl)-2H-chromen-3-yl)benzene-1,3-diol
Synonym	More Synonyms

Description	Dehydroglyasperin D inhibits rat and human Aldose Reductase (AR) (IC50: 62.4 μM and 176.2 μM respectively). Dehydroglyasperin D has anti-obesity, antioxidant effects. Dehydroglyasperin D shows anti-inflammatory activity by inhibiting COX-2 expression and the MLK3 signaling pathway. Dehydroglyasperin D also inhibits melanin synthesis. Dehydroglyasperin D is a prenylated flavonoid that can be isolated from Glycyrrhiza uralensi[1][2][3].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Aldose Reductase Research Areas >> Inflammation/Immunology Signaling Pathways >> Immunology/Inflammation >> COX Research Areas >> Metabolic Disease
Target	COX-2[1]
References	[1]. Lee YS, et al. Aldose reductase inhibitory compounds from Glycyrrhiza uralensis. Biol Pharm Bull. 2010;33(5):917-21. [2]. Jung SK, et al. MLK3 is a novel target of dehydroglyasperin D for the reduction in UVB-induced COX-2 expression in vitro and in vivo. J Cell Mol Med. 2015 Jan;19(1):135-42. [3]. Baek EJ, et al. Dehydroglyasperin D Suppresses Melanin Synthesis through MITF Degradation in Melanocytes. J Microbiol Biotechnol. 2022 Aug 28;32(8):982-988.

Density	1.2±0.1 g/cm3
Boiling Point	557.9±50.0 °C at 760 mmHg
Molecular Formula	C₂₂H₂₄O₅
Molecular Weight	368.42
Flash Point	291.2±30.1 °C
Exact Mass	368.162384
PSA	68.15000
LogP	6.18
Vapour Pressure	0.0±1.6 mmHg at 25°C
Index of Refraction	1.605
InChIKey	QHJJASRUTXHRAL-UHFFFAOYSA-N
SMILES	COc1cc2c(c(OC)c1CC=C(C)C)C=C(c1ccc(O)cc1O)CO2

Hazard Codes	Xi

4-[(R)-5,7-Dimethoxy-6-(3-methyl-but-2-enyl)-1-benzopyran-3-yl]-benzene-1,3-diol

4-((R)-5,7-Dimethoxy-6-(3-methyl-but-2-enyl)-1-benzopyran-3-yl)-benzene-1,3-diol

1,3-Benzenediol, 4-[5,7-dimethoxy-6-(3-methyl-2-buten-1-yl)-2H-1-benzopyran-3-yl]-

4-[5,7-Dimethoxy-6-(3-methyl-2-buten-1-yl)-2H-chromen-3-yl]-1,3-benzenediol

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Dehydroglyasperin D
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Dehydroglyasperin D
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.