Guanosine,2'-deoxy-1-methyl-

Modify Date: 2024-01-03 11:58:48

Guanosine,2'-deoxy-1-methyl- Structure
Guanosine,2'-deoxy-1-methyl- structure
Common Name Guanosine,2'-deoxy-1-methyl-
CAS Number 5132-79-6 Molecular Weight 281.27
Density 1.88g/cm3 Boiling Point 690.7ºC at 760mmHg
Molecular Formula C11H15N5O4 Melting Point N/A
MSDS N/A Flash Point 371.5ºC

 Use of Guanosine,2'-deoxy-1-methyl-


2’-Deoxy-N1-methylguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name n1-methyl-2'-deoxyguanosine
Synonym More Synonyms

 Guanosine,2'-deoxy-1-methyl- Biological Activity

Description 2’-Deoxy-N1-methylguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Density 1.88g/cm3
Boiling Point 690.7ºC at 760mmHg
Molecular Formula C11H15N5O4
Molecular Weight 281.27
Flash Point 371.5ºC
Exact Mass 281.11200
PSA 128.42000
Index of Refraction 1.823
Storage condition 2-8°C

 Synonyms

2'-deoxy-1-methylguanosine
2-Amino-3-methyl-3H-imidazole-4-carboxylic acid ethyl ester
1-N-methyl-2-amino imidazole-5-carboxylic acid ethyl ester
1-methyl-2'-deoxy-guanosine
2-Amino-5-carbethoxy-1-methyl-imidazol
1-Methyl-2-amino-5-carbethoxyimidazol
ethyl 2-amino-1-methyl-1H-imidazole-5-carboxylate
1-N-methyl-2'-deoxyguanosine
1-methyldeoxyguanosine