Cenderitide
Modify Date: 2024-01-22 17:17:22
Cenderitide structure
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Common Name | Cenderitide | ||
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| CAS Number | 507289-11-4 | Molecular Weight | 3745.27 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C158H263N49O50S3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of CenderitideCenderitide is a potent agonist of particulate guanylyl cyclase receptor (pGC). Cenderitide is a natriuretic peptide (NP) composed of C-type natriuretic peptide (CNP) fused to the C-terminus of Dendroaspis natriuretic peptide (DNP). Cenderitide activates both pGC-A and pGC-B, activates the second messenger cGMP, suppresses aldosterone, and preserves GFR without reducing blood pressure. Cenderitide can be used for heart failure research[1][2][3]. |
| Name | Cenderitide |
|---|
| Description | Cenderitide is a potent agonist of particulate guanylyl cyclase receptor (pGC). Cenderitide is a natriuretic peptide (NP) composed of C-type natriuretic peptide (CNP) fused to the C-terminus of Dendroaspis natriuretic peptide (DNP). Cenderitide activates both pGC-A and pGC-B, activates the second messenger cGMP, suppresses aldosterone, and preserves GFR without reducing blood pressure. Cenderitide can be used for heart failure research[1][2][3]. |
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| Related Catalog | |
| In Vitro | Cenderitide has antiproliferative, anti-fibrotic, and anti-hypertrophic properties[1]. |
| In Vivo | In vivo in normal canines, Cenderitide (10, 50, and 100 ng/kg) is a potent cGMP stimulator that has renal enhancing and cardiac unloading effects, with less reduction of blood pressure[1][4]. |
| Molecular Formula | C158H263N49O50S3 |
|---|---|
| Molecular Weight | 3745.27 |