Rotundifuran

Modify Date: 2025-08-25 16:59:25

Rotundifuran structure	Common Name	Rotundifuran
	CAS Number	50656-65-0	Molecular Weight	362.50300
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₂H₃₄O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Rotundifuran

Rotundifuran, a labdane type diterpene, is isolated from Vitex rotundifolia. Rotundifuran can inhibit the cell cycle progression and induce apoptosis in human myeloid leukaemia cells[1][2].

Name	[(1R,3R,4R,4aS,8aS)-4-[2-(furan-3-yl)ethyl]-4-hydroxy-3,4a,8,8-tetramethyl-2,3,5,6,7,8a-hexahydro-1H-naphthalen-1-yl] acetate
Synonym	More Synonyms

Description	Rotundifuran, a labdane type diterpene, is isolated from Vitex rotundifolia. Rotundifuran can inhibit the cell cycle progression and induce apoptosis in human myeloid leukaemia cells[1][2].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer
References	[1]. Ko WG, et, al. Rotundifuran, a labdane type diterpene from Vitex rotundifolia, induces apoptosis in human myeloid leukaemia cells. Phytother Res. 2001 Sep; 15(6):535-7. [2]. Li WX, et, al. Labdane-type diterpenes as new cell cycle inhibitors and apoptosis inducers from Vitex trifolia L. J Asian Nat Prod Res. 2005 Apr; 7(2): 95-105.

Description

Rotundifuran, a labdane type diterpene, is isolated from Vitex rotundifolia. Rotundifuran can inhibit the cell cycle progression and induce apoptosis in human myeloid leukaemia cells[1][2].

Related Catalog

Signaling Pathways >> Apoptosis >> Apoptosis

Research Areas >> Cancer

References

[1]. Ko WG, et, al. Rotundifuran, a labdane type diterpene from Vitex rotundifolia, induces apoptosis in human myeloid leukaemia cells. Phytother Res. 2001 Sep; 15(6):535-7.

[2]. Li WX, et, al. Labdane-type diterpenes as new cell cycle inhibitors and apoptosis inducers from Vitex trifolia L. J Asian Nat Prod Res. 2005 Apr; 7(2): 95-105.

Molecular Formula	C₂₂H₃₄O₄
Molecular Weight	362.50300
Exact Mass	362.24600
PSA	59.67000
LogP	4.74740
Storage condition	2-8℃

Rotundifuran

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Purity: 98.0%
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Rotundifuran

Use of Rotundifuran

Names

Rotundifuran Biological Activity

Chemical & Physical Properties

Synonyms

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