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Rotundifuran

Names

[ CAS No. ]:
50656-65-0

[ Name ]:
Rotundifuran

[Synonym ]:
Rotundifuran
UNII-T2UY9AYG4O

Biological Activity

[Description]:

Rotundifuran, a labdane type diterpene, is isolated from Vitex rotundifolia. Rotundifuran can inhibit the cell cycle progression and induce apoptosis in human myeloid leukaemia cells[1][2].

[Related Catalog]:

Signaling Pathways >> Apoptosis >> Apoptosis
Research Areas >> Cancer

[References]

[1]. Ko WG, et, al. Rotundifuran, a labdane type diterpene from Vitex rotundifolia, induces apoptosis in human myeloid leukaemia cells. Phytother Res. 2001 Sep; 15(6):535-7.

[2]. Li WX, et, al. Labdane-type diterpenes as new cell cycle inhibitors and apoptosis inducers from Vitex trifolia L. J Asian Nat Prod Res. 2005 Apr; 7(2): 95-105.

Chemical & Physical Properties

[ Molecular Formula ]:
C22H34O4

[ Molecular Weight ]:
362.50300

[ Exact Mass ]:
362.24600

[ PSA ]:
59.67000

[ LogP ]:
4.74740

[ Storage condition ]:
2-8℃


Related Compounds

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