Shishijimicin A
Modify Date: 2025-12-01 09:27:00
Shishijimicin A structure
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Common Name | Shishijimicin A | ||
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| CAS Number | 503860-50-2 | Molecular Weight | 981.18 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C46H52N4O12S4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Shishijimicin AShishijimicin A is a novel antitumor agent found from the Ascidian Didemnum proliferum. Shishijimicin A shows anti-tumor activity with highly potent cytotoxicities[1][2]. |
| Name | Shishijimicin A |
|---|
| Description | Shishijimicin A is a novel antitumor agent found from the Ascidian Didemnum proliferum. Shishijimicin A shows anti-tumor activity with highly potent cytotoxicities[1][2]. |
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| Related Catalog | |
| In Vitro | Shishijimicin A (compound 1) (0.47-2.0 pg/mL) shows high cytotoxicity for 3Y1, Hela and P388 cells[1]. Shishijimicin A (0.13-1000 nM) shows high cytotoxicity for MES SA, MES SA DX and HEK 293T cells[2]. Cell Cytotoxicity Assay[1] Cell Line: 3Y1, Hela and P388 cells Concentration: 0.47-2.0 pg/mL Incubation Time: Result: Showed IC50 values of 2.0, 1.8, and 0.47 pg/mL for 3Y1, Hela and P388 cells, respectively. Cell Cytotoxicity Assay[2] Cell Line: MES SA, MES SA DX and HEK 293T cells Concentration: 0.13-1000 nM Incubation Time: Result: Showed IC50 values of 0.13, >1000, and 0.016 nM for MES SA, MES SA DX and HEK 293T cells, respectively. |
| References |
| Molecular Formula | C46H52N4O12S4 |
|---|---|
| Molecular Weight | 981.18 |
| InChIKey | FVNYJZKDBPDHIP-NATOZQEOSA-N |
| SMILES | COC(=O)NC1=C2C(=CCSSSC)C(O)(C#CC=CC#CC2OC2OC(C)C(SC)(C(=O)c3nccc4c3[nH]c3ccc(O)cc34)C(O)C2OC2CC(OC)C(NC(C)C)CO2)CC1=O |