Cucurbitacin IIB
Modify Date: 2025-08-27 08:10:54
Cucurbitacin IIB structure
|
Common Name | Cucurbitacin IIB | ||
|---|---|---|---|---|
| CAS Number | 50298-90-3 | Molecular Weight | 520.698 | |
| Density | 1.22±0.1 g/cm3 | Boiling Point | 668.4±55.0 °C at 760 mmHg | |
| Molecular Formula | C30H48O7 | Melting Point | 158-159ºC | |
| MSDS | N/A | Flash Point | 372.0±28.0 °C | |
Use of Cucurbitacin IIBCucurbitacin IIb is an active component isolated from Hemsleya amabilis, induces apoptosis with anti-inflammatory activity. Cucurbitacin IIb inhibits phosphorylation of STAT3, JNK and Erk1/2, enhances the phosphorylation of IκB and NF-κB (p65), blocks nuclear translocation of NF-κB (p65) and decreases mRNA levels of IκBα and TNF-α[1]. |
| Name | Cucurbitacin IIB |
|---|---|
| Synonym | More Synonyms |
| Description | Cucurbitacin IIb is an active component isolated from Hemsleya amabilis, induces apoptosis with anti-inflammatory activity. Cucurbitacin IIb inhibits phosphorylation of STAT3, JNK and Erk1/2, enhances the phosphorylation of IκB and NF-κB (p65), blocks nuclear translocation of NF-κB (p65) and decreases mRNA levels of IκBα and TNF-α[1]. |
|---|---|
| Related Catalog | |
| References |
| Density | 1.22±0.1 g/cm3 |
|---|---|
| Boiling Point | 668.4±55.0 °C at 760 mmHg |
| Melting Point | 158-159ºC |
| Molecular Formula | C30H48O7 |
| Molecular Weight | 520.698 |
| Flash Point | 372.0±28.0 °C |
| Exact Mass | 520.340027 |
| PSA | 135.29000 |
| LogP | 1.92 |
| Vapour Pressure | 0.0±4.6 mmHg at 25°C |
| Index of Refraction | 1.577 |
| InChIKey | VVBWBGOEAVGFTN-LPQIEKFGSA-N |
| SMILES | CC(C)(O)CCC(=O)C(C)(O)C1C(O)CC2(C)C3CC=C4C(CC(O)C(O)C4(C)C)C3(C)C(=O)CC12C |
| Storage condition | 2-8°C |
| Precursor 1 | |
|---|---|
| DownStream 0 | |
| 19-Norlanost-5-ene-11,22-dione, 2,3,16,20,25-pentahydroxy-9-methyl-, (2β,3α,9β,10α,16α)- |
| (1S,2S,4R,9β,16α)-1,2,16,20,25-Pentahydroxy-9,10,14-trimethyl-4,9-cyclo-9,10-secocholest-5-ene-11,22-dione |
| 25-deacetyl hemslecin A |
| 22,23-dihydrocucurbitacin F |
| Estr-5-en-11-one, 17-[(1R)-1,5-dihydroxy-1,5-dimethyl-2-oxohexyl]-2,3,16-trihydroxy-4,4,9,14-tetramethyl-, (2β,3α,9β,10α,16α,17β)- |
| 23,24-Dihydrocucurbitacin F |
| dihydrocucurbitacin F |
| CucurbitacinⅡb |
| Cucurbitacin Ⅱb |
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- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: Cucurbitacin IIB
- Price: Check
- Purity: 98.0%
- Delivery: 10 Day
- Contact: Yang
- Email: sales@echemcloud.com
- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: Cucurbitacin IIB
- Price: ￥988.0/20mg
- Purity: 98.0%
- Delivery: 1 Day
- Contact: Liu jia
- Email: 2130147988@qq.com
- DC Chemicals Limited
- China
- Product Name: Cucurbitacin Iib
- Price: $280.0/20mg
- Purity: 98.0%
- Delivery: 3 Day
- Contact: Tony Cao
- Email: sales@dcchemicals.com
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: CUCURBITACIN IIB
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Delivery: Inquiry
- Contact: Ms Wang
- Email: enquiry@dycnchem.com
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Price: ￥6015/1g
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