2-Hydroxy-4-methylbenzoic acid

Modify Date: 2025-08-20 11:24:42

2-Hydroxy-4-methylbenzoic acid structure	Common Name	2-Hydroxy-4-methylbenzoic acid
	CAS Number	50-85-1	Molecular Weight	152.147
	Density	1.3±0.1 g/cm3	Boiling Point	315.2±30.0 °C at 760 mmHg
	Molecular Formula	C₈H₈O₃	Melting Point	173-177 °C(lit.)
	MSDS	Chinese USA	Flash Point	158.6±21.1 °C
	Symbol	GHS07	Signal Word	Warning

Use of 2-Hydroxy-4-methylbenzoic acid

4-Methylsalicylic acid is a salicylic acid. 4-Methylsalicylic acid derivative is a selective tissue-nonspecific alkaline phosphatase (TNAP) and intestinal alkaline phosphatase (IAP) inhibitor[1].

Name	4-methylsalicylic acid
Synonym	More Synonyms

Description	4-Methylsalicylic acid is a salicylic acid. 4-Methylsalicylic acid derivative is a selective tissue-nonspecific alkaline phosphatase (TNAP) and intestinal alkaline phosphatase (IAP) inhibitor[1].
Related Catalog	Signaling Pathways >> Apoptosis >> IAP Research Areas >> Inflammation/Immunology
References	[1]. Mumtaz A, et al. Bisthioureas of pimelic acid and 4-methylsalicylic acid derivatives as selective inhibitors of tissue-nonspecific alkaline phosphatase (TNAP) and intestinal alkaline phosphatase (IAP): Synthesis and molecular docking studies. Bioorg Chem. 2020 Aug;101:103996.

Density	1.3±0.1 g/cm3
Boiling Point	315.2±30.0 °C at 760 mmHg
Melting Point	173-177 °C(lit.)
Molecular Formula	C₈H₈O₃
Molecular Weight	152.147
Flash Point	158.6±21.1 °C
Exact Mass	152.047348
PSA	57.53000
LogP	2.52
Vapour Pressure	0.0±0.7 mmHg at 25°C
Index of Refraction	1.600

2-Hydroxy-4-methylbenzoic acid MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GP3920100

CHEMICAL NAME :: 2,4-Cresotic acid

CAS REGISTRY NUMBER :: 50-85-1

BEILSTEIN REFERENCE NO. :: 2208140

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C8-H8-O3

MOLECULAR WEIGHT :: 152.16

WISWESSER LINE NOTATION :: QVR BQ D1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1800 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: APSXAS Acta Pharmaceutica Suecica. (Apotekarsocieteten-Farmacevtiska Foereningen, Box 1136, S-111, 81 Stockholm, Sweden) V.1- 1964- Volume(issue)/page/year: 7,289,1970

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302-H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi:Irritant;
Risk Phrases	R36/37/38
Safety Phrases	S26-S37/39
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	GP3920100
HS Code	2918219000

Precursor 10
CAS#:99-94-5 4-Methylbenzoic acid CAS#:7697-25-8 2-Chloro-4-meth... CAS#:124-38-9 Carbon dioxide CAS#:108-39-4 m-Cresol
CAS#:298-14-6 Potassium hydro... CAS#:5331-40-8 Pyridinium,1-[2... CAS#:6921-64-8 2'-Hydroxy-4'-m... CAS#:71321-26-1 2-hydroxy-2-(2-...
CAS#:14002-90-5 2H-1-Benzopyran... CAS#:698-27-1 2-Hydroxy-4-met...
DownStream 10
CAS#:4670-56-8 Methyl 2-hydrox... CAS#:14504-07-5 2-Acetoxy-4-met... CAS#:4619-74-3 Tribromometacresol CAS#:29666-53-3 2,5-Cyclohexadi...
CAS#:6623-35-4 5-bromo-2-hydro... CAS#:6623-36-5 3,5-dibromo-2-h... CAS#:19814-69-8 3,6-dimethylxan... CAS#:220438-80-2 (4-Carboxy-3-et...
CAS#:108-39-4 m-Cresol CAS#:124-38-9 Carbon dioxide

HS Code	2918290000
Summary	HS: 2918290000 other carboxylic acids with phenol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) VAT:17.0% MFN tariff:6.5% General tariff:30.0%

[New highly phosphorescent heteroleptic tris-cyclometalated iridium (III) complexes: synthesis and photophysical characterization].

Guang Pu Xue Yu Guang Pu Fen Xi 30(1) , 170-3, (2010)

New heteroleptic tris-cyclometalated iridium(III) complexes (ppy)2 Ir(LX) (ppy==2-phenylpyridine, LX==Sal (salicylic acid), Msal (4-methylsalicylic acid), FSal(4-trifluoro methyl salicylic acid)) was ...

Inhibition of a medium chain acyl-CoA synthetase involved in glycine conjugation by carboxylic acids.

Biochem. Pharmacol. 52 , 1643-1646, (1996)

Molecular characteristics of carboxylic acids were investigated for the ability to inhibit a purified medium chain acyl-CoA synthetase, using hexanoic acid as a substrate. Salicylic acid, 4-methylsali...

2-Hydroxy-4-methylbenzoic acid,m-Cresotic acid

4-Methylsalicylic acid

2-Hydroxy-4-methyl-benzoic acid

EINECS 200-068-3

2-Hydroxy-p-toluic Acid

Benzoic acid, 2-hydroxy-4-methyl-

m-Cresotic acid

2-Hydroxy-4-methylbenzoic acid

MFCD00002454

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: 2-Hydroxy-4-methylbenzoic acid
Price: Check
Purity: 99.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: 2-Hydroxy-4-methylbenzoic acid
Price: ￥348.0/100g ￥118.0/25g
Purity: 99.0%
Delivery: 2 Day
Contact: Liu jia
Email: 2130147988@qq.com

DC Chemicals Limited
China
Product Name: 4-Methylsalicylic acid
Price: ￥Inquiry/100mg ￥Inquiry/250mg ￥Inquiry/1g
Purity: 98.0%
Delivery: 10 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 4-Methylsalicylic acid
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

Henan Tianfu Chemical Co., Ltd.
China
Product Name: 4-Methylsalicylic acid
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Delivery: Inquiry
Contact: Anson
Email: info@tianfuchem.com

Get all suppliers and price by the below link:

2-Hydroxy-4-methylbenzoic acid suppliers

2-Hydroxy-4-methylbenzoic acid price

2-Hydroxy-4-methylbenzoic acid

Use of 2-Hydroxy-4-methylbenzoic acid

Names