N,N'-(Ethane-1,2-diyl)bis(2-(4-(tert-butyl)phenoxy)acetamide)

Modify Date: 2024-01-09 16:53:19

N,N'-(Ethane-1,2-diyl)bis(2-(4-(tert-butyl)phenoxy)acetamide) structure	Common Name	N,N'-(Ethane-1,2-diyl)bis(2-(4-(tert-butyl)phenoxy)acetamide)
	CAS Number	494830-67-0	Molecular Weight	440.58
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₆H₃₆N₂O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of N,N'-(Ethane-1,2-diyl)bis(2-(4-(tert-butyl)phenoxy)acetamide)

NIC3 is a selective nucleus accumbens-associated protein-1 (NAC1) inhibitor, binds to the conserved Leu-90 of NAC1, prevents its homodimerization, and leads to proteasomal NAC1 degradation. Anti-cancer activity[1].

Name	NIC3

Description	NIC3 is a selective nucleus accumbens-associated protein-1 (NAC1) inhibitor, binds to the conserved Leu-90 of NAC1, prevents its homodimerization, and leads to proteasomal NAC1 degradation. Anti-cancer activity[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
Target	NAC1[1]
References	[1]. Wang X, et al. Identification of a small-molecule compound that inhibits homodimerization of oncogenic NAC1 protein and sensitizes cancer cells to anticancer agents. J Biol Chem. 2019 May 17. pii: jbc.RA119.007664.

Molecular Formula	C₂₆H₃₆N₂O₄
Molecular Weight	440.58

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