N,N'-(Ethane-1,2-diyl)bis(2-(4-(tert-butyl)phenoxy)acetamide)

Modify Date: 2025-09-05 17:46:43

N,N'-(Ethane-1,2-diyl)bis(2-(4-(tert-butyl)phenoxy)acetamide) structure	Common Name	N,N'-(Ethane-1,2-diyl)bis(2-(4-(tert-butyl)phenoxy)acetamide)
	CAS Number	494830-67-0	Molecular Weight	440.58
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₆H₃₆N₂O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of N,N'-(Ethane-1,2-diyl)bis(2-(4-(tert-butyl)phenoxy)acetamide)

NIC3 is a selective nucleus accumbens-associated protein-1 (NAC1) inhibitor, binds to the conserved Leu-90 of NAC1, prevents its homodimerization, and leads to proteasomal NAC1 degradation. Anti-cancer activity[1].

Name	NIC3

Description	NIC3 is a selective nucleus accumbens-associated protein-1 (NAC1) inhibitor, binds to the conserved Leu-90 of NAC1, prevents its homodimerization, and leads to proteasomal NAC1 degradation. Anti-cancer activity[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
Target	NAC1[1]
References	[1]. Wang X, et al. Identification of a small-molecule compound that inhibits homodimerization of oncogenic NAC1 protein and sensitizes cancer cells to anticancer agents. J Biol Chem. 2019 May 17. pii: jbc.RA119.007664.

Molecular Formula	C₂₆H₃₆N₂O₄
Molecular Weight	440.58
InChIKey	ZVSHISOEPMAPLF-UHFFFAOYSA-N
SMILES	CC(C)(C)c1ccc(OCC(=O)NCCNC(=O)COc2ccc(C(C)(C)C)cc2)cc1

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.