dihydralazine

Modify Date: 2024-01-08 20:19:55

dihydralazine Structure
dihydralazine structure
Common Name dihydralazine
CAS Number 484-23-1 Molecular Weight 190.205
Density 1.6±0.1 g/cm3 Boiling Point 419.9±28.0 °C at 760 mmHg
Molecular Formula C8H10N6 Melting Point 180ºC
MSDS N/A Flash Point 207.7±24.0 °C

 Names

Name (4-hydrazinylphthalazin-1-yl)hydrazine
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.6±0.1 g/cm3
Boiling Point 419.9±28.0 °C at 760 mmHg
Melting Point 180ºC
Molecular Formula C8H10N6
Molecular Weight 190.205
Flash Point 207.7±24.0 °C
Exact Mass 190.096695
PSA 108.34000
LogP 0.73
Vapour Pressure 0.0±1.0 mmHg at 25°C
Index of Refraction 1.810

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TH8849900
CHEMICAL NAME :
Phthalazine, 1,4-dihydrazino-
CAS REGISTRY NUMBER :
484-23-1
BEILSTEIN REFERENCE NO. :
0183442
LAST UPDATED :
199703
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C8-H10-N6
MOLECULAR WEIGHT :
190.24
WISWESSER LINE NOTATION :
T66 CNNJ BMZ EMZ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
106 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
300 mg/kg
TOXIC EFFECTS :
Vascular - BP lowering not characterized in autonomic section
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intravenous
DOSE :
250 ug/kg
SEX/DURATION :
female 32 week(s) after conception
TOXIC EFFECTS :
Reproductive - Specific Developmental Abnormalities - cardiovascular (circulatory) system

MUTATION DATA

TYPE OF TEST :
Mutation test systems - not otherwise specified
TEST SYSTEM :
Bacteria - Escherichia coli
DOSE/DURATION :
125 ug/tube
REFERENCE :
ABPLAF Acta Biochimica Polonica. (Polish Biochemical Society, Posteura 3, 01-093 Warsaw, Poland) V.1- 1954- Volume(issue)/page/year: 42,291,1995

 Safety Information

HS Code 2933990090

 Synthetic Route

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

1,4-Phthalazinedione, 2,3-dihydro-, dihydrazone
Dihydralazin
Nepresol
1,4-dihydrazinophthanazine
1,4-Phthalazinedione, 2,3-dihydro-, dihydrazone, (1Z,4Z)-
1,4-Dihydrazinophthalazine
Nepresolin
Dihydrallazine
Dihydrallazin
4-Hydrazino-1-hydrazono-1,2-dihydrophthalazine
phthalazine, 1,4-bis(hydrazino)-
Phthalazine, 1,4-bis(hydrazinyl)-
1,4-dihydrazinophtalazine
(1Z,4E)-1,4-Dihydrazono-1,2,3,4-tetrahydrophthalazine
Nepressol
Hypopresol
1,4-bis(hydrazino)phthalazine
1,4-Phthalazinedione, 2,3-dihydro-, dihydrazone, (1Z,4E)-
(1Z,4Z)-1,4-Dihydrazono-1,2,3,4-tetrahydrophthalazine
Ophthazin
dihydralazine
1,4-dihydrazinylphthalazine