9-Phenanthrol

Modify Date: 2024-01-03 11:49:51

9-Phenanthrol Structure
9-Phenanthrol structure
Common Name 9-Phenanthrol
CAS Number 484-17-3 Molecular Weight 194.23
Density 1.2±0.1 g/cm3 Boiling Point 404.5±14.0 °C at 760 mmHg
Molecular Formula C14H10O Melting Point 139-143ºC
MSDS Chinese USA Flash Point 197.7±12.0 °C

 Use of 9-Phenanthrol


9-Phenanthrol (9-Hydroxyphenanthrene) is a potent and selective human TRPM4 inhibitor, with an IC50 of 20 μM. 9-Phenanthrol can be used for the research of ischemia-reperfusion injury[1][2].

 Names

Name 9-phenanthrol
Synonym More Synonyms

 9-Phenanthrol Biological Activity

Description 9-Phenanthrol (9-Hydroxyphenanthrene) is a potent and selective human TRPM4 inhibitor, with an IC50 of 20 μM. 9-Phenanthrol can be used for the research of ischemia-reperfusion injury[1][2].
Related Catalog
References

[1]. Wang J, et, al. 9-Phenanthrol, a TRPM4 inhibitor, protects isolated rat hearts from ischemia-reperfusion injury. PLoS One. 2013 Jul 25;8(7):e70587.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 404.5±14.0 °C at 760 mmHg
Melting Point 139-143ºC
Molecular Formula C14H10O
Molecular Weight 194.23
Flash Point 197.7±12.0 °C
Exact Mass 194.073166
PSA 20.23000
LogP 3.94
Vapour Pressure 0.0±1.0 mmHg at 25°C
Index of Refraction 1.754
Storage condition Refrigerator

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
SF8288000
CHEMICAL NAME :
9-Phenanthrol
CAS REGISTRY NUMBER :
484-17-3
BEILSTEIN REFERENCE NO. :
2047057
LAST UPDATED :
199612
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C14-H10-O
MOLECULAR WEIGHT :
194.24
WISWESSER LINE NOTATION :
L B666J HQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :
DNA damage
TEST SYSTEM :
Rodent - hamster Kidney
DOSE/DURATION :
5 mg/L
REFERENCE :
BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 20,1297,1971

 Safety Information

Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi: Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S37/39
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS SF8288000
HS Code 2906299090

 Synthetic Route

 Customs

HS Code 2906299090
Summary 2906299090 other aromatic alcohols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

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 Synonyms

9-Phenanthrol
Phenanthren-9-ol
MFCD00082298
EINECS 207-602-4
9-Phenanthrenol
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