ANY1
Modify Date: 2024-09-10 10:09:44
ANY1 structure
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Common Name | ANY1 | ||
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| CAS Number | 482574-02-7 | Molecular Weight | 537.082 | |
| Density | 2.6±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C15H7Br2N9O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of ANY1ANY1 (FosA inhibitor ANY1) is a small molecule active site inhibitor of FosA (metal-dependent glutathione S-transferase) with IC50 of 5.1 uM (K. pneumoniae FosA); binds to wild-type and mutant FosA3 measured by fluorescence quenching with Kd vales of 440-4880 nM; potentiates Fosfomycin (FOM) activity in representative Gram-negative pathogens. |
| Name | 6,6'-(4-Nitro-1H-pyrazole-3,5-diyl)bis(3-bromopyrazolo[1,5-a]pyrimidin-2(1H)-one) |
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| Synonym | More Synonyms |
| Description | ANY1 (FosA inhibitor ANY1) is a small molecule active site inhibitor of FosA (metal-dependent glutathione S-transferase) with IC50 of 5.1 uM (K. pneumoniae FosA); binds to wild-type and mutant FosA3 measured by fluorescence quenching with Kd vales of 440-4880 nM; potentiates Fosfomycin (FOM) activity in representative Gram-negative pathogens. |
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| References | References 1. Tomich AD, et al. Antimicrob Agents Chemother. 2019 Jan 14. pii: AAC.01524-18. View Related Products by Target Bacterial |
| Density | 2.6±0.1 g/cm3 |
|---|---|
| Molecular Formula | C15H7Br2N9O4 |
| Molecular Weight | 537.082 |
| Exact Mass | 534.898743 |
| LogP | 0.00 |
| Index of Refraction | 2.068 |
| Pyrazolo[1,5-a]pyrimidin-2(1H)-one, 6,6'-(4-nitro-1H-pyrazole-3,5-diyl)bis[3-bromo- |
| 6,6'-(4-Nitro-1H-pyrazole-3,5-diyl)bis(3-bromopyrazolo[1,5-a]pyrimidin-2(1H)-one) |