Thymidine-13C5,15N

Modify Date: 2024-01-09 10:47:26

Thymidine-13C5,15N Structure
Thymidine-13C5,15N structure
Common Name Thymidine-13C5,15N
CAS Number 478511-40-9 Molecular Weight 249.17900
Density N/A Boiling Point N/A
Molecular Formula C10H14N2O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Thymidine-13C5,15N


Thymidine-13C5,15N is the 13C and 15N labeled Thymidine. Thymidine, a specific precursor of deoxyribonucleic acid, is used as a cell synchronizing agent. Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replicatio

 Names

Name thymidine (deoxyribose-13c5

 Thymidine-13C5,15N Biological Activity

Description Thymidine-13C5,15N is the 13C and 15N labeled Thymidine. Thymidine, a specific precursor of deoxyribonucleic acid, is used as a cell synchronizing agent. Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replicatio
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

[2]. Chen G, et al. Cell Synchronization by Double Thymidine Block. Bio Protoc. 2018 Sep 5;8(17).;FIRKET H, et al. Autoradiographic visualization of synthesis of deoxyribonucleic acid in tissue culture with tritium-labelled thymidine. Nature. 1958 Jan 24;181(4

 Chemical & Physical Properties

Molecular Formula C10H14N2O5
Molecular Weight 249.17900
Exact Mass 249.10100
PSA 104.55000
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